Skip to main content

Top 10 Best Pain Relief Creams

Written by Andrew Le, MD

UpdatedJuly 23, 2024

At some point in our lives, we have all felt pain, which is an unpleasant sensation. Finding respite can be difficult, regardless of the cause—overexertion, chronic illness, or accident. For people looking for a topical remedy for their suffering, pain relief creams are a common choice. Without the need for oral medication, these creams are intended to be applied directly to the afflicted area to provide targeted treatment.

There are many different options available on the market for pain relief lotions. Certain lotions are made especially for joint pain, while others are made for aches and pains in general or muscular soreness. It might be difficult to choose the perfect product when there are so many options.


HemRid Maximum Strength Lidocaine Cream

Editor's Choice

HemRid Maximum Strength Lidocaine Cream

With HemRid Maximum Strength Lidocaine Cream, get relief quickly. With its smooth integration into your daily regimen, this mixture guarantees long-lasting comfort. For all-encompassing hemorrhoidal relief, it's your go-to source for soothing Aloe Vera and quick-acting lidocaine. Accept comfort; do not allow discomfort to stop you.

See price on Amazon

We personally evaluated HemRid Maximum Strength Lidocaine Cream, and we vouch for its effectiveness in relieving hemorrhoidal pain quickly and persistently. The cream is a practical option for on-the-go treatment due to its smooth application and quick absorption.

With HemRid, take charge of your comfort. For maximum relief, smoothly integrate it into your everyday regimen. With its soothing Aloe Vera infusion and quick-acting lidocaine, this cream provides a comprehensive method of treating hemorrhoidal irritation.

Pros

  • Maximum Strength Lidocaine: Benefit from the potent pain-numbing effects of Lidocaine, providing unparalleled relief for discomfort associated with hemorrhoids.
  • Quick and Lasting Relief: HemRid acts swiftly to alleviate pain, ensuring long-lasting comfort and promoting a speedy recovery from hemorrhoidal discomfort.
  • Soothing Aloe Vera: Enriched with Aloe Vera, this cream not only relieves pain but also soothes and nourishes the affected area, promoting overall healing.

Cons

  • Possible Sensitivity: Some individuals may experience mild sensitivity, so it's advisable to perform a patch test before regular use.
  • Avoidance in Certain Conditions: Consultation with a healthcare professional is recommended for those with specific health conditions or allergies.
  • External Use Only: This cream is designed for external use only; avoid contact with eyes and mucous membranes.

FRANKINCENSE & MYRRH Arthritis Pain Therapy Lotion

FRANKINCENSE & MYRRH Arthritis Pain Therapy Lotion

See price on Amazon

This lotion features a blend of essential oils including frankincense and myrrh, known for their anti-inflammatory properties. It also contains aloe vera and shea butter to hydrate and repair the skin while providing relief from joint and muscle pain.

I found the lotion to be effective in reducing arthritis pain and providing a soothing sensation upon application. The texture is non-greasy and absorbs well into the skin, making it suitable for daily use without leaving residue. It works relatively quickly to alleviate discomfort, though the intensity of relief may vary depending on the individual.

Pros

  • Contains natural ingredients like frankincense and myrrh.
  • Provides dual benefits of pain relief and skin hydration.
  • Non-greasy texture and pleasant scent.
  • Convenient packaging for easy application.

Cons

  • Relief may be temporary and require frequent reapplication.
  • Some users may find the scent of essential oils strong.

Penetrex Joint & Muscle Therapy

Penetrex Joint & Muscle Therapy

See price on Amazon

Having used Penetrex ourselves, we can attest to its superior quality. The cream is simple to use, sinks into the skin right away, and leaves no behind. We like that it is vegan, cruelty-free, and paraben-free. It also doesn't smell strongly, which is quite pleasing to us.

We have had alleviation from back, neck, and knee discomfort using Penetrex. It also functions well with other therapies; we've used it with cold packs and heating pads. We administered the lotion as directed, three to four times a day for seven to ten days, and thereafter as needed.

Pros

  • Penetrex is a . whole-body therapy cream. that's effective for joint and muscle discomfort at the source.
  • The proprietary blend of natural ingredients, including arnica, vitamin B6, and . MSM. , penetrates deeply into the skin.
  • Penetrex is a non-greasy, non-sticky, and non-staining soothing cream without the burn, freeze, or strong odor of other products.

Cons

  • Some users might find the price a bit steep.
  • Penetrex might not work for everyone.
  • It might take a few days to see the full benefits of the product.

Blue Emu Muscle and Joint Deep Soothing Original Analgesic Cream

Blue Emu Muscle and Joint Deep Soothing Original Analgesic Cream

See Price on Amazon

For individuals who require immediate relief, Blue Emu Muscle and Joint Deep Soothing Original Analgesic Cream is an excellent choice because it quickly penetrates the skin and has a deep penetrating effect. 91% of research participants saw improvement, demonstrating the cream's clinical veracity.

Applying the cream every day is not only advised but safe as well. For two weeks, apply liberally two to three times a day; after that, as needed. Use the 12 oz Original Super Strength Cream to relieve dry, chapped, or worn skin in addition to its soothing properties.

Pros

  • The emu oil formula helps ingredients like Aloe Vera, MSM, and Glucosamine absorb directly to your joints and muscles.
  • The cream can be applied to multiple areas of the body, including back, neck, shoulders, elbows, wrists, knees, hips, feet, hands, and ankles.
  • The cream is odor-free and non-greasy, making it irritation-free.

Cons

  • The cream may not be as effective for severe pain relief as other products on the market.
  • The recommended application of 2-3 times daily may not be convenient for everyone.
  • The cream may not be suitable for those with sensitive skin.

Bengay Ultra Strength Topical Pain Relief Cream

Bengay Ultra Strength Topical Pain Relief Cream

See price on Amazon

After using Bengay Ultra Strength Topical Pain Relief Cream, we were able to effectively relieve mild arthritis and muscular soreness. Three painkilling components in the cream—methyl salicylate, menthol, and camphor—combine to offer exceptionally potent pain relief.

Bengay Ultra Strength Topical Pain Relief Cream's ability to thoroughly penetrate and deliver long-lasting pain relief is one of its strongest features. We discovered that the lotion had an immediate and long-lasting effect on our muscle soreness.

The non-greasy composition is ideal for on-the-go treatment because it is simple to administer and comes in a handy tube. However, some people may find the potent aroma overpowering, and some may experience a warming or cooling feeling from the cream.

Pros

  • With three pain-relieving ingredients, this cream provides ultra-strong relief for minor arthritis, muscle, and joint pain.
  • Bengay Ultra Strength Topical Pain Relief Cream penetrates deeply, providing long-lasting pain relief.
  • This non-greasy cream is easy to apply and comes in a convenient tube for on-the-go relief.

Cons

  • The strong scent may be overwhelming for some users.
  • The cream may cause a warming or cooling sensation that some users may find uncomfortable.
  • The cream may not be suitable for individuals with sensitive skin.

Blue Emu Muscle and Joint Deep Soothing Original Analgesic Cream

Blue Emu Muscle and Joint Deep Soothing Original Analgesic Cream

See Price on Amazon

If you have muscular or joint pain, this cream is a game-changer. Without leaving a greasy aftertaste, the deeply penetrating composition swiftly penetrates beneath the skin to deliver immediate relief. This cream has been used on many body areas, and it has always had positive effects.

Another major benefit for people who don't want to put up with the menthol stench that frequently accompanies pain treatment creams is that the cream has no smell. Additionally, because it's non-greasy, you don't have to be concerned about any residue getting on your furniture or clothing.

Pros

  • The emu oil formula is naturally powerful and quickly absorbed by joints and muscles.
  • The cream can be applied to various parts of the body for daily soothing assistance.
  • It's odor-free and non-greasy, making it an irritation-free application.

Cons

  • Some users may not prefer the texture of the cream.
  • The cream may not work as effectively for severe or chronic pain.
  • It may take some time to see noticeable results.

Tylenol Maximum Strength 4% Lidocaine Pain Relieving Cream

Tylenol Maximum Strength 4% Lidocaine Pain Relieving Cream

See price on Amazon

The focused pain relief of Tylenol Maximum Strength 4% Lidocaine Pain Relieving Cream impressed us during our recent trial. Because the cream is made without a prescription and contains maximum dose lidocaine, it's a good choice for people with mild muscular and joint aches.

Our favorite feature was the mess-free, massaging rollerball applicator, which made it easy for us to apply the cream exactly where we needed it. One benefit of the cream was that it absorbed rapidly and left no residue behind.

Pros

  • The cream provides penetrating pain relief and numbs away minor joint and muscle pain.
  • The mess-free, massaging rollerball applicator allows for precise application.
  • The rapid-absorbing, non-sticky cream leaves no residue and is fragrance- and dye-free.

Cons

  • The numbing effect may not last as long as some users would like.
  • The cream may not be as effective for severe or chronic pain.
  • Some users may find the rollerball applicator difficult to use on certain areas of the body.

Aspercreme with Lidocaine Maximum Strength Pain Relief Cream

Aspercreme with Lidocaine Maximum Strength Pain Relief Cream

See price on Amazon

Over the years, we've tried a number of pain relief creams, and Aspercreme with Lidocaine Maximum Strength Pain Relief Cream is among the best. More pain receptors are targeted by the active ingredient, lidocaine, than by any other over-the-counter topical painkiller. It is a potent numbing agent. This implies that a variety of mild aches and pains, such as sprains, strains, and arthritis, can be relieved by it.

The speed at which Aspercreme works is one of our favorite things about it. In just a few minutes, the cream can provide numbing relief by rapidly penetrating muscles and joints. Furthermore, Aspercreme doesn't leave a greasy or sticky aftertaste, in contrast to several other pain treatment creams. Additionally, it has no smell, which is fantastic if you don't want to smell like menthol or other overpowering fragrances.

Pros

  • Targets more pain receptors than any other over-the-counter topical analgesic
  • Fast-acting formula works in minutes and provides relief for hours
  • Odor-free and non-greasy for discreet and comfortable relief

Cons

  • Some users may experience mild irritation or burning
  • May not be strong enough for severe or chronic pain
  • Lidocaine may not be suitable for everyone, so check with your doctor before using

Arvesa Natural Hemp Cream

Arvesa Natural Hemp Cream

See price on Amazon

We have personally experienced small aches and pains being relieved by Arvesa Natural Hemp Cream. The cream doesn't leave a greasy aftertaste and smells good. Those with sensitive skin or excruciating discomfort, however, could find it inappropriate. All things considered, we suggest this product to anyone searching for a natural cream for pain treatment.

Pros

  • The cream is made with natural ingredients, including hemp oil, arnica montana, turmeric, aloe vera, emu oil, boswellia extract, and menthol. It's a safe and natural formula that doesn't contain GMOs or gluten.
  • This product is designed to provide maximum strength pain relief and is suitable for use on various parts of the body, including hips, joints, neck, back, elbows, fingers, hands, and knees. It's great for post-workout recovery and athletes.
  • Arvesa Natural Hemp Cream is made in the USA with premium quality ingredients. It has a lightweight texture that's non-greasy and doesn't leave any unpleasant odor. It can also double as a skin moisturizer.

Cons

  • Some users may find the cream to be ineffective for severe pain relief.
  • The cream may not be suitable for those with sensitive skin or allergies to any of the ingredients.
  • The packaging of the product may not be as sturdy as some users would like.

Dragon Ultra-Strength Pain Relief Cream

Dragon Ultra-Strength Pain Relief Cream

See price on Amazon

After using Dragon Ultra-Strength Pain Relief Cream, we discovered that it is effective in treating localized pain in the joints, ligaments, and muscles brought on by sprains, bruises, and arthritis. The cream is simple to use and absorbs rapidly, offering immediate relief for aches and pains in the muscles and joints, arthritis, and other sore spots on the back, knee, elbow, wrist, and other regions.

However, some consumers may find the cream's powerful fragrance unpleasant. Furthermore, for certain individuals' pain treatment needs, it might not be as helpful as other products. It's also important to note that some users may find the tingling sensation the cream causes to be bothersome.

Pros

  • Provides quick relief for minor muscle discomfort, back pain, sprains, neck aches, and muscle fatigue
  • Rapidly absorbs into the skin
  • Contains potent analgesics, including Camphor and Menthol

Cons

  • Has a strong smell
  • Might not work as effectively as other products for some users
  • Can cause a tingling sensation on the skin

Buying Guide

When looking for the best pain relief cream, there are a few factors to consider to ensure you choose a product that will effectively relieve your pain. Here are some features to look for when selecting a pain relief cream:

Active Ingredients

The active ingredients in a pain relief cream are the compounds that provide the pain relief. Look for creams that contain ingredients such as menthol, capsaicin, or lidocaine, as these have been shown to effectively relieve pain. It is important to note that different ingredients work better for different types of pain, so it is essential to choose a cream that targets your specific type of pain.

Texture and Application

The texture of the cream and how it is applied can also impact its effectiveness. Creams that are too thick or greasy can be difficult to apply and may not absorb into the skin properly. On the other hand, creams that are too thin may not provide enough coverage. Look for creams that have a smooth texture and are easy to apply.

Safety and Side Effects

Before purchasing a pain relief cream, it is essential to check for any potential safety concerns or side effects. Some creams may contain ingredients that can cause an allergic reaction, so it is important to read the label carefully. Additionally, some creams may interact with other medications or medical conditions, so it is important to consult with a healthcare professional before using a new pain relief cream.

Price

Price is also an important factor to consider when choosing a pain relief cream. While some creams may be more expensive than others, it is important to remember that a higher price does not necessarily mean a better product. Look for creams that provide effective pain relief at a reasonable price.

Frequently Asked Questions

What is considered the most effective over-the-counter pain relief cream?

When it comes to over-the-counter pain relief creams, there are several options available. However, the most effective one varies depending on the type of pain you are experiencing. Some of the most popular options include creams containing menthol, camphor, or capsaicin. These ingredients work by numbing the pain or by creating a warming or cooling sensation that can help alleviate discomfort.

For muscle aches, what is the strongest non-prescription muscle relaxant cream available?

When it comes to muscle aches, creams containing methyl salicylate or menthol are considered to be the strongest non-prescription muscle relaxant creams available. These ingredients work by providing a warming or cooling sensation that can help relax tight muscles and alleviate pain.

What are the top-rated anti-inflammatory creams currently on the market?

Some of the top-rated anti-inflammatory creams currently on the market include those containing diclofenac, ibuprofen, or naproxen. These ingredients work by reducing inflammation and alleviating pain.

Affiliate Disclosure:
The links provided may earn us a small commission at no additional cost to you if you choose to purchase the recommended product. This support allows our research and editorial team to continue providing high-quality recommendations. As a participant in the Amazon Services LLC Associates Program, an affiliate advertising initiative, we are able to earn advertising fees through providing links to products on Amazon.com. Please rest assured that we only recommend high-quality products.