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Top 8 Best Black Seed Oils with Highest Thymoquinone

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Written by Andrew Le, MD.
Medically reviewed by
Clinical Physician Assistant, Summit Health
Last updated June 7, 2024

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Black seed oil or nigella sativa oil is an oil that has been in the market for a very long time and is used for medical purposes. Black seed oil, derived from the seeds of the Nigella Sativa plant, contains a key compound known as thymoquinone – an antioxidant with anti-inflammatory effects. Most of the health benefits of black seed oil are attributed to thymoquinone, which is an active ingredient in the oil.

Currently, there is increased production of black seed oil and it is widely available in the market due to increased demand. Nonetheless, not all black seed oils are the same and some of them may contain more thymoquinone than the other. When seeking the best black seed oil with the highest level of thymoquinone, two key factors should be considered: the concentration of thymoquinone present and the quality of the oil.

In order to find the best black seed oils in terms of thymoquinone content and general quality, we dedicated several hours to research and testing. In the subsequent sections of this review, we will provide you with our opinion on the best black seed oil that contains the highest concentration of thymoquinone.

Top 3 Best Black Seed Oils with Highest Thymoquinone

  1. Triquetra Health Black Seed Oil Extract Capsules
  2. Organic Black Seed Oil by PRIME NATURAL
  3. Black Seed Oil TQ Advanced

In this article, we have compared different types of black seed oils and recommended the best ones with the highest concentration of thymoquinone. Thymoquinone is one of the active ingredients found in black seed oil that is said to possess immune boosting and anti-inflammatory effects. Based on the above analysis, we have the following list of the best black seed oils that are packed with thymoquinone to guide you.

Triquetra Health Black Seed Oil Extract Capsules

The Editor's Choice

Triquetra Health's Black Seed Oil Extract Capsules offer noticeable overall health improvements due to their CO2 extraction and nutrient-rich nigella sativa seeds. The standout: high Thymoquinone content, five times more than competitors, supporting immune, joint, skin, and gut health.

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If you are interested in a high-quality capsule supplement that contains black seed oil extract, we highly recommend the Triquetra Health Black Seed Oil Extract Capsules.

Pros

  • The highest concentration of Thymoquinone available on the market at 20%.
  • Each capsule contains 50mg of Thymoquinone, which is five times more than competitors.
  • Made from the cleanest CO2 extraction process and the most nutrient-dense nigella sativa seeds.

Cons

  • The capsules may have a slightly funky taste.
  • Not suitable for those who are allergic to nigella sativa.
  • Some users may experience mild stomach discomfort when taking the capsules.

The capsules are made through the purest CO2 extraction method used on the highest quality nigella sativa seeds with all the bioactives passed in their natural state.

What makes Triquetra Health’s Black Seed Oil Extract Capsules different from other supplements is the presence of Thymoquinone in its composition. This suggests that each capsule has 50mg of Thymoquinone, a concentration five times more potent than its competitors. Black seed oil contains a nutrient called Thymoquinone that offers numerous benefits to the body’s immune system, inflammatory systems, joint pains, hair and skin, and the gut.

One is that the capsules will have a slightly unpleasant taste and this may not go down well with the users. Also, if one has an allergy to nigella sativa then he/she should refrain from taking these capsules. Some of the users may also develop a mild form of stomach upset once they have consumed the capsules.

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Anyone interested in obtaining a natural supplement that can address respiratory, immune, cardiovascular, and digestive issues as well as skin, hair, and nails should purchase this product.

Pros

  • Contains powerful antioxidants, NIGELLONE, THYMOQUINONE, and more for respiratory and immune system benefits
  • Best vegan option for cardiovascular and digestive health with Omega 3, 6, 9, and amino acids
  • Can be used topically on skin, hair, and nails for natural restoration

Cons

  • Strong smell and taste may not be pleasant for some users
  • Some users may experience an aftertaste
  • May take time to see noticeable improvement in health and restoration

In our experience, Organic Black Seed Oil by PRIME NATURAL has proven to be effective in enhancing our respiratory and immune systems, scalp, and hair health. It is a USDA organic certified, cold pressed virgin unrefined pure natural product that does not contain alcohol and hexane extraction, additives, and fillers.

This product is packaged in an elegant dark amber glass bottle with a pump, glass dropper, and a tamper-proof seal at the cap for accurate dispensing of the oil. The bottle size is 120ml or 4oz and it is a convenient size for daily usage.

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If you are in search of a black seed oil that is high in thymoquinone then Black Seed Oil TQ Advanced is a product to look at.

Pros

  • Contains 5% thymoquinone, making it one of the most potent black seed oils available.
  • Delivered in raw form, maintaining its full bioactive components.
  • Vegan, GMO-free, filler-free, soy-free, dairy-free, and preservative-free.

Cons

  • Has a strong taste that may be unpleasant for some.
  • The dropper may leak, causing waste.
  • Some users may experience digestive issues.

The oil is very easy to consume, and the dropper cap ensures the right amount is used. But the flavoring is quite powerful and might take some time to get accustomed to.

What we love about this product is that it is vegan and not diluted with fillers, soy, dairy, or preservatives. We also like that it is presented in its raw form so that it retains its total potency of bioactive compounds.

Despite not coming across any adverse effects ourselves, others may face digestive problems. Furthermore, the dropper can leak which is a waste.

All in all, if you are interested in getting the best black seed oil with a focus on the concentration of thymoquinone, then the Black Seed Oil TQ Advanced deserves your attention.

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If you need a strong black seed oil supplement, the Triquetra Health TQ-Advanced Black Seed Oil capsules are perfect for you.

Pros

  • With 5% thymoquinone, these capsules are one of the most potent black seed oil products available.
  • The oil is derived from the true Nigella sativa species of black seed and delivered in raw form, maintaining its full bioactive components.
  • Triquetra Health is committed to quality, with their product being vegan, GMO-free, filler-free, soy-free, dairy-free, and preservative-free. The oil is third-party tested for over 100+ contaminates and microbials, and it is manufactured in the USA in a high-quality GMP regulated facility.

Cons

  • Some users may find the capsules difficult to swallow due to their size.
  • The product may be too potent for those who are new to taking black seed oil supplements.
  • The cost per capsule may be higher compared to other black seed oil products on the market.

These capsules are easy to swallow and do not even have a concentrated taste or odor that stays in your mouth. The company can be praised for its quality and reliability; its product is tested by a third-party, and they are made in the USA.

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For an effective black seed oil that contains thymoquinone, Anor Foods Black Seed Oil is an excellent choice.

Pros

  • Organically grown and cold-pressed for high potency and quality nutrition
  • Boosts the immune system and may help with muscle and joint fatigue
  • May improve skin and hair health and support healthy digestive and heart function

Cons

  • Has a strong, bitter, and spicy flavor that may not be palatable for everyone
  • Comes in a glass bottle that may not be practical for travel or outdoor activities
  • Some users have reported issues with the packaging, such as leaks or loose caps

The oil has a rather specific and intense taste that may be off-putting to some, however, we like that it is made from organically grown and non-GMO crops, and contains no pesticides.

Another advantage we have enjoyed is bowel movement and digestion. We observed that skin becomes clearer and shinier and hair becomes smoother and silkier. It has been used internally as a supplement, but it can also be applied externally for skin and hair problems.

Another benefit of Anor Foods Black Seed Oil is that it helps in strengthening the immune system. We have been administering it during winter and everyone feels that it has assisted in boosting our immunity and preventing illnesses. We also understand that it may assist in muscle and joint fatigue, this is beneficial for any person involved in physical activity or sports.

Nevertheless, the following are the drawbacks: Unfortunately, it has a rather powerful and rather pungent flavor that will not suit everybody. It is also packed in a glass bottle, which could be inconvenient for travelling or other physical activities. Some users have claimed they have found that the bottle was leaking or the cap was not firmly sealed, so one needs to be gentle when handling the bottle.

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If you are interested in getting genuine black seed oil with a high concentration of thymoquinone then NutriONN Organic Black Seed Oil is ideal for you.

Pros

  • Comes in an FDA approved and completely safe PET bottle, which is shatterproof, 100% recyclable, and lightweight.
  • Certified organic, extracted from non-GMO plants, and unrefined.
  • Contains up to 3% thymoquinone, which is the highest potency on the market.

Cons

  • The plastic bottle may not be the preferred choice for some customers.
  • The taste may not be suitable for everyone.
  • The product may not work for everyone.

The oil is extracted from non-genetically modified plants and is organically certified which means we are using a healthy and safe product. Due to the high concentration of thymoquinone in the oil, it can be recommended to anyone who wants to have a healthy immune system.

Another advantage of NutriONN Organic Black Seed Oil is that it is good for hair, skin as well as nails. The oil is packed with essential nutrients and fatty acids that help improve the health and appearance of our hair, nails, and skin.

In summary, we strongly encourage anyone who wants the best black seed oil with a high level of thymoquinone to purchase NutriONN Organic Black Seed Oil. The 60-day 100% money-back assurance guarantees that you can use the product with no obligation.

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If you are seeking a good black seed oil supplement that contains a high level of thymoquinone, you should try out High Potency Black Seed Oil from Purity Products.

Pros

  • This supplement contains double the strength of thymoquinone compared to other formulas, making it a powerful antioxidant booster for your body's defense system.
  • The advanced cold press technology used in the manufacturing process ensures that you get the maximum benefit from the carefully cultivated Mediterranean Nigella sativa plants.
  • The product is manufactured in FDA-inspected facilities that are 3rd-party certified and audited by the Quality Assurance Department for compliance with Good Manufacturing Practices (cGMP).

Cons

  • The product is only available in mini softgels, which may not be suitable for people who have difficulty swallowing pills.
  • The recommended dosage is one softgel per day, which may not be enough for people who require higher doses of black seed oil.
  • The product is relatively expensive compared to other black seed oil supplements on the market.

It comes in the form of a softgel which is very easy to swallow and the dosage is one softgel a day.

What we like about this product is that it has a high concentration of thymoquinone, which is a compound found in black seed oil that has multiple health benefits such as being antioxidant and anti-inflammatory. It guarantees that the thymoquinone is not damaged in any way through cold press technology utilized in the production of the juice.

Yet another thing that we like about this product is that it is made with quality and safety in mind. The manufacturing facilities are FDA-insured and third-party accredited for cGMP. The operations include procurement of raw materials, manufacturing processes, packaging, labeling, and even the analytical testing done in clean areas for product purity and potency.

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If you want to improve your immune system, heart health, joint health, hair, and skin, then Adalin Black Seed Oil Liquid is a great choice for you.

Pros

  • The black seed oil is cold-pressed to preserve the valuable content of black cumin seeds.
  • It is produced in a GMP-certified facility in Turkey, ensuring the highest quality.
  • The oil is rich in Omega 3 6 9, antioxidants, vitamins A, C, and B, as well as various minerals such as calcium, potassium, magnesium, and zinc.

Cons

  • The taste is strong and may not be suitable for everyone.
  • Some users reported allergic reactions after using the oil.
  • The price may be higher than other black seed oils on the market.

It comes in the form of a soft gel which is very easy to swallow and the dosage is one soft gel a day.

What we like about this product is that it has a high concentration of thymoquinone, which is a compound found in black seed oil that has multiple health benefits such as being antioxidant and anti-inflammatory. It guarantees that the thymoquinone is not damaged in any way through cold press technology utilized in the production of the juice.

Yet another thing that we like about this product is that it is made with quality and safety in mind. The manufacturing facilities are FDA-insured and third-party accredited for cGMP. The operations include procurement of raw materials, manufacturing processes, packaging, labeling, and even the analytical testing done in clean areas for product purity and potency.

Buying Guide

When searching for the best black seed oil that contains a high amount of thymoquinone, the following factors must be considered. Here are some features to look for:

Purity

Ensure that the oil is of the highest quality and does not contain any other compound or is preserved in any way. Always opt for cold-pressed oils and those that have not been processed through heat because heat destroys the beneficial fatty acids present in the oil.

Thymoquinone Content

Since thymoquinone is the major constituent in black seed oil, it is wise to select a product that contains a high level of thymoquinone. It is recommended to look for products that declare the percentage of thymoquinone on the label and use products with not less than 2% of thymoquinone.

Quality

Select a product that a third party has analyzed for quality and purity before it hits the market. This serves to ensure that the product has all the ingredients listed on its label and that it does not contain any harmful substances.

Packaging

There is also a way in which the packaging of the black seed oil can influence the quality of the product. The products should be packed in black opaque containers to shield the oil from light and air since these affect the quality of the oil.

Price

When it comes to making a purchase, price is not always everything, but it is useful to compare the price per ounce of the product.

Frequently Asked Questions

1. What is the highest concentration of thymoquinone in black seed oil?

It is important to understand that the amount of TQ in black seed oil may differ significantly depending on the brand and extraction method. Nonetheless, some brands boast of having up to 5% TQ in their black seed oil.

2. Which brand of black seed oil has the highest TQ level?

Some of the brands of black seed oil that are in the market today contain higher TQ levels than others. Nevertheless, it is crucial to mention that TQ levels may differ with the batch and the extraction procedure. These brands that claim to have high TQ levels include Amazing Herps Kiva and Sweet Sunnah.

3. What is the recommended percentage of thymoquinone in black seed oil?

No specific percentage of TQ in black seed oil is advised as it differs depending on the situation of the affected individual. However, some studies show that an increased TQ concentration might be beneficial for human health.

4. Are there any side effects to taking high doses of thymoquinone?

Thymoquinone is usually safe, however, taking large amounts could lead to side effects including nausea, vomiting, and diarrhea. As with any supplement, it is advisable to seek medical advice before using any supplement.

5. Can Ethiopian black seed oil capsules provide the same benefits as the oil?

Although the benefits of Ethiopian black seed oil capsules may be the same as those of the oil, it is crucial to consider the TQ content and the quality of the capsules before using them.

6. What are the benefits of taking TQ-advanced black seed oil?

TQ-advanced black seed oil could also have other health benefits than TQ since it contains a higher concentration of TQ. Possible advantages include boosting the immune system, decreasing inflammation, and enhancing respiratory health. Thus, more studies are still necessary in order to determine the impact of TQ-advanced black seed oil.

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Clinical Physician Assistant, Summit Health
Jeff brings to Buoy 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medicine....
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