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Top 16 Best Digestive Enzyme Supplements

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Written by Andrew Le, MD.
Medically reviewed by
Last updated September 4, 2024

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Discovering the best digestive enzyme supplements can significantly enhance your digestive health and overall well-being. Whether you struggle with occasional indigestion, bloating, or nutrient absorption issues, the right enzyme supplement can make a world of difference. These powerful supplements work by breaking down food more efficiently, ensuring your body absorbs essential nutrients optimally. Here, we will look at the best digestive enzyme products on the market, their benefits and ingredients, and what sets them apart. Discover how to improve digestion and overall wellbeing by identifying the most effective digestive enzyme supplement for you.

Top 3 Best Digestive Enzyme Supplements

  1. HUM Flatter Me Supplement for Daily Bloating
  2. Nutricost Digestive Enzymes 620mg, 120 Capsules
  3. Ultra Probiotic - 60B SBO Probiotic


HUM Flatter Me Supplement for Daily Bloating

Editor's Choice

HUM Flatter Me Supplement stands out for its blend of 18 digestive enzymes, aiding in the breakdown of proteins, carbs, and fats. Ingredients like ginger and fennel seed support digestion. Consider it for a happier gut.

See Price of HUM Flatter Me on Amazon

Are you sick and weary of enduring constant gas and discomfort in your digestive system? HUM Flatter Me Supplement for Daily Bloating is the only supplement you need. This potent blend includes eighteen full-spectrum digestive enzymes that help your body break down food so that vital nutrients are absorbed more effectively. Your ticket to a happier, healthier gut is this 30-day supply, which is jam-packed with powerful nutrients like peppermint, fennel seed, and ginger.

Pros

  • Comprehensive blend of 18 digestive enzymes for optimal food breakdown
  • Contains ginger, fennel seed, and peppermint for enhanced nutrient absorption
  • Helps alleviate daily bloating and digestive discomfort

Cons

  • Some users may find the price point slightly higher than other digestive supplements on the market
  • Results may vary and could take time to notice significant improvements

HUM Flatter Me Supplement is unique in that it contains a broad spectrum of 18 digestive enzymes in one comprehensive mixture. To ensure that your body can effectively absorb the nutrients it needs from meals, these enzymes function in unison to break down proteins, carbs, and fats. In addition, the use of peppermint, ginger, and fennel seed aids in supporting digestion and reducing bloating and pain.

It's crucial to remember that those who are allergic to specific ingredients should use caution when taking this product. Also, even though HUM Flatter Me Supplement has several advantages over other digestive aids on the market, some customers could find the price tag to be a little bit expensive. Furthermore, individual outcomes may differ, as with any dietary supplement, and it may take some time to see results.

See Price of Nutricost Digestive Enzymes on Amazon

If you're looking for a high potency digestive enzyme supplement, Nutricost Digestive Enzymes may be worth considering.

Pros

  • One capsule per serving
  • Non-GMO and gluten-free
  • Made in a GMP compliant, FDA registered facility

Cons

  • May cause stomach cramps for some due to the bromelain content
  • May not be effective for everyone
  • Some users may experience more gas and bloating

We’ve been using Nutricost Digestive Enzymes for quite some time now and the outcomes are satisfactory for us. Since this is a convenient dietary supplement that only requires one capsule for each serving, it does not present difficulties in its use. Additionally, knowing that the product is non-GMO and gluten-free helps to eliminate any concerns.

One thing that has been known about this product is that consumers have complained of stomach upsets because of bromelain. Also, it should be mentioned that in our case, it was helpful; however, it might not be the same for everybody. Some people may also have increased flatulence.

See Price of Physician's Ultra Probiotic on Amazon

Unlock optimal digestion with Ultra Probiotic - 60B SBO Probiotic. This digestive enzyme powerhouse boasts a potent blend of 60 billion soil-based organisms (SBOs) per serving, providing unparalleled support for gut health.

Pros

  • Potent SBO Blend: Harness the power of 60 billion soil-based organisms, carefully selected for their digestive benefits. This diverse blend promotes a robust microbiome, essential for overall gut well-being.
  • Digestive Enzyme Boost: Ultra Probiotic goes beyond conventional probiotics by including digestive enzymes. These enzymes enhance nutrient absorption, reduce bloating, and support a smoother digestive process.
  • Gut Harmony: Achieve digestive balance with this supplement. Whether you struggle with irregularity or discomfort after meals, Ultra Probiotic promotes gut harmony, leading to improved overall digestive health.

Cons

  • Relatively pricey
  • Optimal results come with regular use.

We have personally experienced life-changing results from including Ultra Probiotic into our daily routines. Say goodbye to digestive problems because this pill promotes long-lasting gut health by addressing problems at their source.

Ultra Probiotic is notable for its dedication to excellence. This supplement has undergone extensive testing to ensure its efficacy and purity, making it a dependable partner on your path to digestive wellbeing.

Accept a life full with digestive energy. With Ultra Probiotic - 60B SBO Probiotic, your secret to a robust and harmonious gut, you may enhance your well-being.

See price of Naturenetics Probiotics on Amazon

Experience Naturenetics Probiotics 30 Billion CFU Guaranteed's transformative power—a revolutionary solution for digestive health. This supplement is the ultimate in digestive enzyme support, with a powerful blend of 30 billion live cultures. Boost your health with the certainty of guaranteed CFUs, which support a healthy gut flora and a strong digestive tract.

Pros

  • Naturenetics delivers a substantial 30 billion CFUs per capsule, ensuring a potent dose of beneficial bacteria to fortify your gut health.
  • This supplement goes beyond the basics, offering a comprehensive blend of probiotic strains that work synergistically to support various aspects of digestion.
  • Rest easy knowing that the 30 billion CFUs are guaranteed until the expiration date, ensuring that you receive the full benefits of this high-potency probiotic.

Cons

  • To maintain the potency of the live cultures, this probiotic supplement needs refrigeration, which might be less convenient for some users.
  • As with any supplement, individual responses may vary. Some users may experience mild digestive adjustments during the initial days of use.

With Naturenetics Probiotics, you can unleash the full potential of your digestive system. We have personally noticed the energizing benefits, which include better digestion, less bloating, and a general improvement in gut health. For individuals looking for a dependable and efficient digestive enzyme boost, this supplement is a natural option because it is devoid of artificial ingredients and preservatives.

Include Naturenetics Probiotics 30 Billion CFU Guaranteed in your daily regimen. Boost your gut health and improve your digestion by trying Naturenetics out now.

See Price of Juna Detox Digestive Enzymes with Probiotics on Amazon

Discover the secret to robust gut health with the best digestive supplement available: Juna Detox Digestive Enzymes with Probiotics. Carefully crafted, it is one of the best options for people who value intestinal health.

Pros:

  • Juna Detox combines digestive enzymes with probiotics, ensuring a holistic approach to digestive health with vegan-friendly ingredients.
  • Experience relief from bloating, cleanse your system, and support digestion while alleviating discomfort and promoting overall gut health.
  • Elevate your immunity and digestive function with this potent blend, crafted to support your body's natural processes and enhance well-being.

Cons:

  • Individuals with difficulty swallowing larger capsules may find this supplement challenging initially, though its benefits far outweigh any temporary inconvenience.
  • Consistent use is recommended to maximize the potential of Juna Detox Digestive Enzymes with Probiotics and unlock lasting gut health benefits.

We can personally attest to the transformational power of the Juna Detox experience, having embarked on it ourselves. This supplement exceeds expectations by providing a well-balanced combination of immune system support and digestive support. It is proof of the values of veganism, holistic health, and individual vitality.

Integrate Juna Detox into your everyday routine. You can achieve better digestive health and general well-being by taking just two capsules every day. Improve your digestive experience by using a supplement that surpasses your health goals and is consistent with your ideals. The Juna Detox combines unmatched digestive health with plant-based potency.

See Price of Double Wood Supplements Digestive Enzymes Now!

If you are determined to look for a standard and effective digestive enzyme supplement to enhance your digestion, Double Wood Supplements Digestive Enzymes could be your choice.

Pros

  • Contains all 10 most essential digestive enzymes, including amylase, lipase, bromelain, lactase, papain, protease, cellulase, maltase, invertase, and glucoamylase.
  • Top 3 pancreatic enzymes included, which break down starches and carbohydrates into sugars, lipids (fats and oils) into glycerol and fatty acids, and proteins into amino acids.
  • VitaZyme Digestive Aid, Double Wood's trademarked blend, helps with bloating relief and supports overall digestive health.

Cons

  • May not work for everyone, as individual results may vary.
  • Some people may experience side effects like nausea or stomach upset.
  • May not be suitable for people with certain medical conditions or those taking certain medications.

For a few weeks now, we have been using Double Wood Supplements Digestive Enzymes and we were fully satisfied with the outcome. These capsules come in rather large sizes yet they can easily be swallowed without leaving any bitter aftertaste.

This supplement includes ten most critical enzymes that work in the digestive system, which is normally tough to see in a single supplement. In addition, three other enzymes; lipase, amylase, and protease which are also common in the pancreas are also incorporated, for the purpose of breaking down starches, carbohydrates, lipids, and proteins.

There is also something we like about this product; the fact that it is manufactured in the USA, is non GMO and gluten free. We also appreciate that capsules are small and can be easily swallowed with no problem or even during working or at a business meeting.

See Price of Zenwise Digestive Enzymes on Amazon

If you're looking for a digestive enzyme supplement that can help you find relief from occasional bloating, gas, and discomfort, Zenwise Digestive Enzymes might be a good option for you.

Pros

  • Formulated to help with digestive discomfort
  • Includes pre and probiotics for gut health
  • Clinically proven probiotic

Cons

  • May cause stomach ache or gas if taken with every meal
  • May cause awkward feeling in the stomach after digestion
  • Contains cellulase, which some may not prefer

Of course, the effect of this supplement is immediate, and the relief from bloating and gas will get you feeling healthy. With enzymes like glucoamylase, amylase, bromelain, cellulase, invertase, lactase, bacterial protease, papain, lipase, and maltase, you will notice an increased regularity in bowel movements which leaves you feeling great in the morning. Furthermore, if you like to indulge in spicy food but always seem to need some relief from bloating and gas, then these supplements are excellent, especially when taken before every meal or snack.

See Price of Doctor's BEST Digestive Enzymes on Amazon

We highly recommend Doctor's BEST Digestive Enzymes for anyone looking for a high potency digestive enzyme supplement that promotes optimal intestinal health.

Pros

  • The complete formula contains friendly bacteria to promote optimal intestinal health.
  • The formula supplies the added support of alpha- galactosidase and beta-glucanase to break down vegetables, beans, and grains.
  • The product is Non-GMO, Gluten-Free, Soy-Free, and Vegetarian.

Cons

  • Exposure to heat or sunlight may lead to melting or damage of the product.
  • The product may arrive warm during summer months.
  • The price is relatively high compared to other digestive enzyme supplements.

We have tried using Doctor’s BEST Digestive Enzymes and can vouch for the fact that it complements the digestive process of fats, protein, and carbohydrates mostly contained in cooked and raw foods. This formulation enhances the action of alpha- galactosidase together with beta-glucanase to help break down vegetables, beans and grains; and glucoamylase plus invertase in the digestion of sugars. Besides, there are friendly bacteria to make this complete formula to be unique for the enhancement of the entire health of our intestines.

See Price of Pure Encapsulations Digestive Enzymes Ultra on Amazon

For those seeking an excellent digestive enzyme supplement that promotes nutritional absorption and bioavailability, we heartily suggest Pure Encapsulations Digestive Enzymes Ultra.

Pros

  • The vegetarian enzymes in this supplement are designed to support nutrient absorption and digestion, making it easier for your body to break down proteins, peptides, polysaccharides, and disaccharides.
  • Pure Encapsulations Digestive Enzymes Ultra contains a dairy enzyme blend that supports the digestion of dairy, sugar, lactose, and certain complex carbs, which can help relieve occasional gas and bloating.
  • This supplement is free from common allergens, artificial or unnecessary ingredients, and GMOs, making it a great choice for those with dietary restrictions or concerns.

Cons

  • Some users may experience mild digestive discomfort or bloating when first starting to use this supplement.
  • The capsules are relatively large, which may be difficult for some users to swallow.
  • This supplement may not be suitable for those with severe digestive issues or medical conditions.

Pure Encapsulations Digestive Enzymes Ultra is an excellent, potent digestive enzyme supplement that can aid in promoting a healthy digestive system and the absorption of nutrients.

See Price of Thorne Advanced Digestive Enzymes on Amazon

We highly recommend Thorne Advanced Digestive Enzymes for anyone looking to improve their gut health and digestion.

Pros

  • Thorne Advanced Digestive Enzymes is a comprehensive formula that contains a blend of hydrochloric acid, pepsin, pancreatin, and ox bile, which can help ease digestive discomfort that may occur after a meal heavy in fat or red meat, when enjoying foods that cause extra gas and bloating, or when partaking in an occasional overindulgence.
  • The supplement promotes nutrient absorption, which benefits absorption of vitamins, minerals, and other nutrients.
  • Thorne is a trusted brand with a long history of collaboration with Mayo Clinic on wellness research and content.

Cons

  • Thorne Advanced Digestive Enzymes is a bit expensive compared to other digestive enzyme supplements.
  • Some users may experience heartburn if they take the supplement on an empty stomach.
  • The capsules are quite large and may be difficult for some people to swallow.

We have personally used Thorne Advanced Digestive Enzymes, and we can attest to its efficacy as a supplement for enhancing gut health and digestion. A combination of digestive enzymes included in the all-inclusive formula may help reduce gastrointestinal distress and enhance nutrient absorption. Although the supplement is somewhat expensive, we think it is well worth the money for anyone trying to get better digestive health.

To prevent heartburn, we do advise buyers to take the supplement with food. Additionally, some people can find it difficult to take the capsules due to their size. All things considered, we heartily endorse Thorne Advanced Digestive Enzymes to anyone wishing to enhance their digestion and gut health.

See Price of Wholesome Wellness Digestive Enzymes on Amazon

This Wholesome Wellness Digestive Enzymes is best for individuals with tough digestion foods or to those who would want to lessen their digestive upset as well as increase their intake of immunity-boosting enzymes.

Pros

  • Ultra-strength 1000 MG dose of clinical-grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics
  • Helps you digest fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies
  • Relieves gas, belly bloating / bloat, constipation, leaky, indigestion, reflux, belching & acid discomfort

Cons

  • May not work for everyone
  • Some users may experience mild side effects such as stomach upset or diarrhea
  • The capsules may be too large for some people to swallow

After utilizing Wholesome Wellness Digestive Enzymes for a few weeks, we must admit that the outcomes have impressed us. A potent combination of prebiotics, probiotics, and digestive enzymes found in the supplement support both a robust immune system and a healthy digestive tract.

The ultra-strength dose of probiotics and digestive enzymes in this supplement is one of our favorites. This product relieves digestive discomfort quickly and contains more than twice the dosage of conventional digestive enzyme supplements. Still, one more thing that has to be mentioned as the advantage of this supplement is the fact that it contributes to digestion of the foods that seem to be difficult for digestion for many people.

See Price of MaryRuth Organics Ultra Digestive Enzymes Capsules on Amazon

For a vegan, gluten-free digestive enzyme supplement that can be used to support digestion, MaryRuth Organics Ultra Digestive Enzymes Capsules could also be worth looking out for.

Pros

  • This supplement is formulated to enhance digestion, especially in those with digestive issues, amplifying nutrient absorption while reducing bloating, gas, and abdominal pain.
  • This extra strength blend of enzymes is formulated to help digest proteins, carbohydrates, fiber, fat, and lactose. They even include enzymes to help relieve occasional gas and bloating, too!
  • Each bottle contains 60 capsules, with a serving size of 1 capsule, and will last 1-2 months. Adults take 1 capsule prior to each meal or as recommended by physician or healthcare professional.

Cons

  • This product contains maltodextrin, which is corn-derived.
  • Some reviewers did not feel much difference after taking this supplement.
  • A few reviewers did not like the taste of this supplement.

After using MaryRuth Organics Ultra Digestive Enzymes Capsules, we discovered that they are simple to take and have no negative side effects. It's crucial to remember that every person has a unique body, therefore outcomes may differ.

We did not find this supplement to have a disagreeable taste, yet other reviewers have expressed distaste for it. Regarding the components, we value that this supplement is free of gluten, dairy, and genetically modified organisms. It is important to note that it contains maltodextrin, which some people may find bothersome.

See Price of Codeage Digestive Enzymes Supplement on Amazon

If you're looking for a digestive enzyme supplement, then Codeage Digestive Enzymes Supplement is definitely worth considering.

Pros

  • All-in-one digestive enzymes solution with probiotics, prebiotics, fermented botanical fruits, and herbs.
  • 14 enzymes all-in-one, including protease, amylase, glucoamylase, diastase, invertase, pectinase, cellulase, hemicellulase, xylanase, lipase, phytase, lactase, alpha-galactosidase, and beta-glucanase enzymes.
  • Contains a fermented organic botanical blend including apple cider vinegar, ginger, kiwi, and turmeric powders.

Cons

  • May not work for everyone.
  • Some people may experience side effects such as gas and bloating.
  • May take some time to see results.

Our digestion has significantly improved after we started taking Codeage Digestive Enzymes Supplement a few weeks ago. With probiotics, prebiotics, fermented botanical fruits, and herbs, this all-in-one digestive enzymes solution is a complete supplement that covers all the bases.

The major plus is that the 14 enzymes are combined in one and we are glad that all are packed in one capsule. The addition of the fermented organic botanical blend is also a good move, and we specifically like its ingredients: apple cider vinegar, ginger, kiwi, and turmeric powders.

Although we haven't had any unfavorable side effects, we've heard that some people might get bloated and have gas. Furthermore, you'll need to exercise patience because it can take some time to notice benefits.

See Price of Source Naturals Essential Enzymes on Amazon

It is normal to experience digestive enzyme deficiency at some point, especially when you eat foods you might not handle well. This is where the Source Naturals digestive enzyme supplements come in. Of course, after trying it, I quickly established that it's a great supplement for several digestive ailments, such as bloating, acidity, and gas.

Pros:

  • Works within 20 minutes
  • Wide variety of enzymes
  • Easy to swallow
  • No noticeable flavor or aftertaste
  • Value for money

Cons:

  • No returns

Furthermore, the enzyme supplement ensures your digestive health remains intact. Of course, this supplement contains protease, lipase, alpha-amylase, amyloglucosidase, hemicellulose, and lactase, which make it great for aiding the digestion of foods like dairy products and red meat. If you have been taking digestive enzymes, you know some brands leave out certain enzymes from their supplements. However, with this brand, you are getting a wide variety of enzymes to aid digestion.

I would recommend that people with issues such as gluten or lactose intolerance might need to take 2 capsules for the enzyme supplement to be worth it. The required dosage indicates 1 pill before each meal but with clear instructions not to exceed 6 pills a day.

See Price of Enzymedica Digest Gold on Amazon

These Enzymedica digestive enzyme supplements are excellent for immediate relief of your indigestion, with unmatched effectiveness. Additionally, they have your back when you eat foods heavy on the stomach, like fried foods. This enzyme supplement provides relief for indigestion, gas, and bloating. Furthermore, the supplement contains amylase, protease, lipase, and lactase that break down complex carbs, fats, and proteins to significantly prevent bloating.

Pros:

  • Effective
  • Easy to swallow
  • Works fast
  • Easily absorbed
  • No discernable flavor

Cons:

  • You will experience some side effects until your body gets used to the enzymes

The dosage indicates taking a pill before a meal. After taking a pill, these digestive enzymes break down all the elements of a typical meal faster, making it easier for your digestive tract. Since the pills are made with naturally occurring digestive enzymes, they work in the same way. Furthermore, I also noticed that even if you forget to take it before you eat, it still works well if you take it right after your meal.

These digestive enzyme supplements are made to remain active throughout the digestive system. Therefore, they are functional in acidic and alkaline environments, so you don't have to worry about indigestion. While I know that this digestive enzyme supplement isn't meant to treat any abdominal pain, it effectively does away with any discomfort and the feeling of being too full after a meal.

See Price of Love Wellness Bye Bye Bloat on Amazon

These are one of the best digestive enzymes infused with fenugreek and organic ginger root. These ingredients help with hormonal water retention and bloating that might make you feel uncomfortable. Additionally, we would recommend it for anyone experiencing any digestive issues and would like some relief.

Pros:

  • Easy to swallow
  • No discernable flavor
  • You can open them into a drink
  • Dairy and gluten-free
  • Vegan-friendly

Cons:

  • Takes a long time to work

The active digestive enzymes in this supplement include amylase, protease, pepsin, lipase, bromelain, and papain which are excellent for the digestion of complex carbohydrates, meat proteins, and saturated fats that could cause severe digestive issues.

I realized that these supplements work better if you take at least 2 every night. You will wake up to regular bowel movements, and your sensitivity to some food groups will be solved. Ensure to take this digestive enzyme supplement as required, or you won't see the difference. However, before you use it, you should know that it takes at least a week to see a major improvement in your digestion. Of course, we wouldn't recommend it to anyone who wants quick results.

Factors to Consider Before Buying the Best Digestive Enzymes

Choosing the best digestive enzymes depends on a few factors. You can base on the following factors:

1) Broad Spectrum Digestive Enzymes

It is critical to find a digestive enzyme supplement with a wide range of enzymes that aid in the breakdown of various nutrients like fiber, fat, carbohydrates, starch, and sugar.Broad-spectrum enzymes have a greater percentage of absorption, a variety of origins and substrates, and a wide range of optimal pH levels. This ensures that the blends offer more advantages than individual enzymes.

Remember, each enzyme has a specific role in the body, and when taken together, they help the digestive system absorb food better. Since your meals combine various food groups, you can easily use digestive enzymes to aid in the digestion of all the essential macronutrients.

Additionally, you can aid in the digestion of all of the macronutrients at once using digestive enzymes because your meals combine various food groups. Plus, you should make it a point to look for a combination of particular enzymes like lipase, lactase, protease, amylase, and cellulase that help the body break down food easily.

Without supplements, you might have problems managing digestive symptoms like bloating, gas, abdominal pain, diarrhea, and fatigue. Proper digestion is important for better nutrient absorption, which supports optimal health.

2) Enzyme Source

Most of the time, plant-based digestive enzymes are preferred over animal and microbial-based varieties due to their efficacy. Since they have low to moderate acidity, they can easily improve gut health. Additionally, enzymes derived from plants will be gentler on the digestive system than those derived from their counterparts, making them more effective since they can alleviate stress on your small intestines.

Vegetarians can also take these enzyme supplements because they don't come from any animal products. Plant-based enzymes are a great option because they are the most potent, but remember, not all people who use digestive enzymes see the same results. Most enzymes on the market are vegetarian, as they contain more active units across a broad range than other types. Remember, animal-derived enzymes are unstable in acidic environments like the stomach and only function within a limited pH range.

3) Form of the Enzyme

Enzyme supplements are more readily available as capsules compared to tablets. Since capsules don't go through a complicated manufacturing process, the majority of the active enzymes remain intact and can be absorbed more efficiently when ingested. In contrast, the complicated processing that goes into making tablets kills some active enzymes, making them less effective in digestion.

If you take the digestive enzyme supplements as a tablet, you should avoid chewing or leaving them in your mouth for a long because they can irritate your cheeks and gums. It is also recommended to use water to swallow the enzyme. When it comes to chewable tablets, ensure to chew them thoroughly before swallowing to ensure maximum absorption during digestion.

Capsules might be a different issue, especially since many people have a problem swallowing them. However, it is okay to open them into a drink like a smoothie if you can't take them whole with water. Just remember not to inhale the powder, as it can irritate your respiratory tract.

4) Naturally Formulated

When looking for digestive enzymes, it is recommended to look for naturally formulated ones. This means you should try to avoidones that contain a lot of fillers, like artificial flavors and colors. Naturally occurring digestive enzyme supplements should also have formulas that may include herbs such as ginger, fennel, or peppermint for further digestive support.

Some naturally formulated digestive enzymes also contain lactase and alpha-galactosidase, which enable lactose digestion. Furthermore, ensure the capsule coating doesn't contain any cellulose or artificial ingredients.

If you want to try naturally fermented foods before taking supplements, try foods like kimchi, ginger, and fresh fruits to support digestion. Of course, if you don't feel better, a good, naturally formulated digestive enzyme supplement is best for your gut health.

5) Enzyme Efficacy

The activity level of a digestive enzyme refers to its rate of reaction when digesting food. Therefore, the higher the activity level, the more remarkable it is in processing your food. Additionally, you will need fewer pills if you choose a supplement with high activity and potency. Furthermore, temperature, concentration, pH, quantity, and substrate influence the enzymes' activity. This means the more potent the activity level, the better its performance.

Most of the time, you can get a rough idea of your enzyme's activity level by how efficiently it works. The majority of digestive enzymes work immediately after taking them. However, you can also know the enzymes' efficiency by the number of individual enzymes in the supplement. If it contains the 4 main digestive enzymes; carbohydrates, proteases, lipases, and nucleases, then it's a good indicator that it's effective.

6) Backed by Research

As a general rule, always look for enzymes that are supported by scientific evidence. Remember, the supplement formulation from a good manufacturer will be based on clinical research. If you are still unsure, you can ask a doctor specializing in gut health or a dietician to evaluate the supplement you intend to purchase. If the supplement you want doesn't check all the boxes, then you must find one that does.

Frequently Asked Questions About the Best Digestive Enzymes

Do digestive enzyme supplements work?

Yes, they do. Digestive supplement enzymes work primarily for people with an enzyme deficiency. A good quality supplement will support digestion, prevent gas and bloating, and help your body to absorb nutrition. Additionally, they relieve other digestive issues that could be caused by chronic pancreatitis or cystic fibrosis.

Of course, to transform food into nutrients that the body can use, digestive enzymes are crucial in breaking down food into molecules small enough to be absorbed by the small intestine and enter the bloodstream. If you have digestive issues like an enzyme deficiency, then the supplements are a good choice.

What is the most effective digestive enzyme?

Determining the most effective digestive enzyme is challenging as effectiveness can vary depending on individual needs and specific digestive issues. However, commonly used enzymes like protease, amylase, lipase, lactase, bromelain, and papain have been shown to be effective for certain conditions such as protein digestion issues, carbohydrate malabsorption, fat malabsorption, lactose intolerance, and general digestive aid. The choice of the most effective enzyme depends on the underlying cause of digestive issues and individual factors. Consulting with a healthcare professional or registered dietitian can help determine the appropriate enzyme or combination of enzymes for individual needs.

What are the 3 most important digestive enzymes?

  1. Protease: Protease is responsible for breaking down proteins into smaller peptides and amino acids. It plays a crucial role in protein digestion and is necessary for the absorption of essential amino acids.
  2. Amylase: Amylase is involved in the digestion of carbohydrates. It breaks down complex carbohydrates, such as starches, into simpler sugars like glucose. This enzyme is essential for the effective breakdown and absorption of carbohydrates.
  3. Lipase: Lipase is responsible for the digestion of dietary fats. It breaks down triglycerides into fatty acids and glycerol, enabling the absorption of fat-soluble vitamins and fatty acids.

These three enzymes collectively cover the digestion of proteins, carbohydrates, and fats, which are the primary macronutrients in our diet. They are essential for optimal digestion and nutrient absorption.

How do I know if digestive enzymes are working?

The body may experience what we refer to as "adjustment effects" rather than actual side effects when starting enzymes. Several of the unpleasant reactions, such as an upset stomach, allergy-like symptoms, or irritability, are actually indications that the enzymes are functioning.

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Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
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