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Maintaining healthy blood circulation is crucial for overall well-being. However, many individuals struggle with poor vascular health, which can lead to issues like high blood pressure, fatigue, and reduced physical performance. Impaired circulation can affect various bodily functions, ultimately impacting energy levels, muscle recovery, and cognitive function. Left unchecked, it can even lead to serious health conditions such as heart disease, stroke, and peripheral artery disease.
Recent data indicates that nearly 45% of adults in the US suffer from high blood pressure, a direct consequence of poor circulation. This alarming statistic highlights the importance of proactive measures to improve blood flow and vascular health. By addressing circulation issues early on, individuals can prevent or mitigate the development of more severe health problems.
Fortunately, supplementing with L-Citrulline, a potent amino acid, can help address these concerns by boosting nitric oxide production and improving blood flow. The top 10 best L-Citrulline supplements reviewed in this article offer a convenient and effective solution for enhancing vascular health, supporting athletic performance, and promoting overall vitality.
Effectiveness of L-Citrulline Supplements in Improving Blood Flow
L-Citrulline, a non-essential amino acid abundantly found in watermelon, plays a significant role in nitric oxide (NO) production, which is crucial for vasodilation and improved blood flow. This amino acid has garnered attention for its potential benefits in enhancing blood circulation and overall cardiovascular health. Various studies have evaluated the effectiveness of L-Citrulline supplements in improving blood flow, especially in different physiological contexts.
Blood Lactate Removal and Exercise Recovery
One study explored L-Citrulline's role in blood-lactate removal kinetics following maximal-effort exercise. Despite the theoretical benefits of L-Citrulline in promoting vasodilation and facilitating lactate clearance, the study found no significant impact on blood lactate kinetics during active recovery.
Additionally, L-Citrulline supplementation did not significantly affect the oxygen cost of exercise, VO2peak, or time-to-exhaustion. These results suggest that L-Citrulline may not significantly enhance blood flow or circulation in the context of exercise recovery.
Impact on Cardiometabolic Health
One study reviewed the potential benefits of L-Citrulline supplementation on cardiometabolic health, particularly in individuals with prehypertension or hypertension. Unlike L-arginine, L-Citrulline is better absorbed and has higher bioavailability, making it more effective in increasing NO synthesis.
The review highlighted that L-Citrulline supplementation could lead to reduced blood pressure and improved endothelial function, both of which are critical for enhancing blood circulation. These findings support the potential of L-Citrulline to positively affect blood flow by promoting vasodilation and cardiovascular health.
Exercise Blood Flow in Older Adults
A study investigated the effects of L-Citrulline on exercise blood flow in older adults. The study demonstrated a modest improvement in femoral blood flow and vascular conductance during lower-limb exercise in older men.
However, no significant changes were observed in women. These findings indicate that L-Citrulline can enhance muscle blood flow during exercise, particularly in older men, which may lead to improved exercise tolerance and overall circulation. This gender-specific response suggests that the benefits of L-Citrulline on blood flow may vary between different demographic groups.
Blood Pressure Regulation
Two systematic reviews and meta-analyses examined the impact of L-Citrulline on blood pressure. Mirenayat et al. found no significant effect of L-Citrulline on both brachial and aortic blood pressure. In contrast, Barkhidarian et al. observed a reduction in systolic blood pressure and a significant reduction in diastolic blood pressure with doses of ≥6 g/day.
These mixed results suggest that while L-Citrulline may help lower blood pressure and improve circulation, the effects are dose-dependent and may vary among individuals. Higher doses seem to be more effective in reducing diastolic blood pressure, thereby potentially enhancing blood flow.
Best L-Citrulline Supplements for Blood Circulation
We have researched the top 10 Best L-Citrulline Supplements for Blood Circulation and selected them based on their effectiveness, ingredient purity, and user feedback. These supplements stand out for their ability to improve vascular health and enhance athletic performance by supporting nitric oxide production, which is crucial for optimal blood flow and muscle function.
BulkSupplements.com L-Citrulline Powder is one of the best L-Citrulline supplements available. It is a convenient and potent option for those maximizing endurance and physical performance.
Each serving contains a substantial 3 grams of L-Citrulline. This supplement offers exceptional quality and efficacy and is tailored to support the diverse needs of fitness enthusiasts, athletes, and those maintaining an active lifestyle. It is also known to provide great vascularity and blood flow.
Pros
- Each serving delivers a substantial 3-gram dose of L-Citrulline, ideal for supporting strength and endurance goals.
- It is versatile and adaptable to various dietary needs and preferences, catering to athletes, fitness enthusiasts, and individuals maintaining an active lifestyle.
- Provides great vascularity and blood flow.
Cons
- A relatively large serving size of 3 grams per serving may require adjustment for those accustomed to smaller doses.
Now Foods L-Citrulline Cardiovascular Health 750mg helps to enhance cardiovascular health and improve metabolic function. Each capsule delivers 750 mg of L-Citrulline.
An amino acid that not only supports the eradication of toxins but improves a healthy immune system and facilitates the healing process. This supplement enhances nitric oxide production and promotes better blood flow, essential for cardiovascular health and efficient nutrient delivery to tissues.
Pros
- The supplement supports heart health by improving blood flow and vascular function through increased nitric oxide production.
- It aids in the urea cycle, helping to remove ammonia, a byproduct of protein digestion, from the body, thus supporting metabolic health.
- L-Citrulline is crucial for immune system support and helps the overall healing process, making it beneficial for recovery and resistance against illnesses.
Cons
- Some people may find capsules more difficult to swallow than powder or liquid supplements.
- Being unflavored might be less appealing to those who prefer flavored supplements.
- The benefits of L-citrulline, particularly for vascular health and detoxification, may require consistent long-term intake to become evident.
Kaged Premium L-Citrulline Powder is among the best L-Citrulline supplements for enhancing muscle pumps, improving muscle vascularity, and boosting nitric oxide levels in the body improving bllod flow. It is 100% plant-based and derived through a fermentation process.
Packaged in a simple, no-frills canister, it contains 100 servings designed to optimize your pre-workout phase. This enables more intense and prolonged workouts, which is crucial for achieving fitness goals.
Pros
- Sourced entirely from plant materials, not from human hair or animal byproducts, making it suitable for vegans and those concerned about animal welfare.
- It provides a full dose of pure L-Citrulline rather than the less effective L-citrulline malate, ensuring maximum effectiveness for enhancing muscle pumps and vascularity.
- Increasing nitric oxide production helps improve blood flow and nutrient delivery, which are crucial for muscle recovery and growth.
Cons
- The lack of flavor might be unappealing to some users who prefer flavored supplements to enhance the taste of their drinks.
- As a powder, it must be mixed with a liquid, which might be less convenient than pre-mixed or capsule supplements.
- Some individuals might experience digestive upset from pure L-Citrulline, especially when taken in high doses.
Doctor's Best L-Citrulline Powder is a scientifically formulated supplement to support vascular health and improve blood circulation. This 200g container of unflavored powder enhances nitric oxide metabolism, which is crucial for maintaining healthy blood vessels and promoting efficient blood flow.
Each serving aims to support muscle protein synthesis and relieve muscle fatigue, making it an excellent choice for athletes and individuals engaged in regular physical activities. It focuses on providing metabolic and muscle maintenance benefits.
Pros
- Enhances nitric oxide production, essential for improving blood circulation and vascular health.
- Supports muscle protein synthesis, aiding in muscle maintenance and recovery after exercise.
- It has no artificial flavors and is purely a straightforward supplement.
Cons
- Unflavored might not appeal to some users who prefer flavored supplements to enhance palatability.
- As a single-ingredient supplement, it may need to be combined with other nutrients or supplements to achieve comprehensive health benefits.
- It may not provide immediate visible results, as effects on nitric oxide levels and muscle fatigue relief can vary by individual.
PrimaForce L-Citrulline Malate Powder ranks among the best L-Citrulline supplements. It is a premium, unflavored pre-workout supplement designed to boost energy, aid recovery, and enhance strength performance. This vegan and non-GMO formula contains 200 grams of L-Citrulline malate in a 2:1 ratio.
It offers a potent dose of this key amino acid to support muscle growth, cardiovascular health and increased blood flow. Each container provides 100 servings, making it both efficient and cost-effective. The product is lab-tested for potency and purity, ensuring athletes and fitness enthusiasts receive only the highest quality ingredients.
Pros
- A pure and clean formulation, lab-tested for quality assurance, with no fillers, additives, or artificial ingredients, caters to health-conscious users.
- Helps with increased blood flow.
- Offers a substantial number of servings per container (100 servings), providing good value for the price.
- Vegan and non-GMO suit various dietary preferences and ensure ethical manufacturing practices.
Cons
- Being unflavored might be less appealing to some users who prefer flavored supplements to mask the natural taste of active ingredients.
- The powder form requires accurate measurement and thorough mixing to ensure proper dosage and prevent clumping.
- As a pure supplement without stimulants, it may not provide the immediate surge of energy that some pre-workout formulas with caffeine or other stimulants do.
Jarrow Formulas® Arginine-Citrulline Sustain™ is a meticulously designed dietary supplement that promotes cardiovascular health and supports nitric oxide production. The product contains a balanced blend of sustained-release arginine citrulline and vitamin C, synergistically enhancing vascular function and improving blood flow.
This supplement, packaged in a 120-tablet container providing a 60-day supply, is geared toward adults looking to maintain or improve vascular health and physical performance. Its main role is facilitating nitric oxide production, a crucial compound for cardiovascular function and muscle relaxation. Thus, it supports arterial health and enhances exercise performance.
Pros
- It contains a balanced mix of arginine and citrulline, essential for producing nitric oxide and enhancing blood flow and cardiovascular health.
- The inclusion of vitamin C not only supports the immune system but also stabilizes nitric oxide, extending its effectiveness in the blood.
- Comes in a sustained-release form, which helps maintain steady levels in the bloodstream for extended benefits throughout the day.
Cons
- The tablets must be taken on an empty stomach, which may be inconvenient for some individuals or lead to digestive discomfort.
- Unflavored tablets may not appeal to everyone, particularly those sensitive to taste or prefer flavored supplements.
- Requires two tablets per serving, which might be a bit much for people who prefer a one-pill dosage.
ALLMAX Essentials CITRULLINE Malate 2:1 stands out as one of the best L-Citrulline supplements. It is designed to enhance endurance and speed up recovery for athletes and fitness enthusiasts. This vegan-friendly powder contains 300 grams of CITRULLINE Malate, providing 150 servings per canister.
Each serving aims to increase blood Arginine levels and improve vascular function and blood flow. Additionally, it helps during intense training and rapidly replenishes energy stores.
It is an excellent choice for those looking to improve training intensity and reduce the sensation of fatigue. Its ability to detoxify muscle tissue by removing ammonia further supports muscle recovery post-exercise.
Pros
- Increases blood Arginine levels effectively, enhancing blood flow and nutrient delivery to muscles.
- Improves vascular function and increases endothelial Nitric Oxide levels, which can lead to better overall cardiovascular health.
- Helps buffer against muscle acidification during intense workouts, allowing for longer and harder training sessions.
- Assists in rapidly replenishing muscle energy stores, enhancing recovery time between workouts.
Cons
- Only available in powder form, which may not be as convenient as capsules or tablets for some users.
- Some users may not prefer the taste of the unflavored powder and might need to mix it with other beverages to mask the flavor.
- Requires mixing, which can be less convenient than ready-to-use supplements.
Horbäach L-Citrulline Capsules are designed to enhance athletic performance by maximizing blood flow and nutrient delivery to muscles. Each serving delivers a robust 2400 mg of L-Citrulline in free form to support those engaged in intense workouts and bodybuilding.
These capsules are ideal for anyone looking to support their fitness goals with a non-essential amino acid that can reduce fatigue and accelerate recovery.
Pros
- Each serving provides a substantial 2400 mg of L-Citrulline, which can significantly enhance nitric oxide production and muscle pump, which is crucial for effective workouts.
- Convenient capsule form makes it easy to consume, especially for those who do not prefer powder supplements.
Cons
- Some users might find the large serving size of three capsules inconvenient or difficult to swallow.
- The unflavored nature of the capsules could be a disadvantage.
- It requires consumption on an empty stomach, which might be inconvenient for some users or cause digestive discomfort.
The XPI L-Citrulline Malate (2:1) Powder is recognized as one of the best l-citrulline supplements for enhancing athletic performance by supporting blood flow and nutrient delivery to muscle tissue.
This product offers 100 servings per 300-gram bottle and is favored by athletes and those focused on muscle development. Each scoop provides an effective dose of L-Citrulline, an amino acid pivotal in the Nitric Oxide cycle, crucial for creating muscle pumps during workouts.
Pros
- It promotes better muscle pumps and overall performance.
- Comes with a scoop for accurate measurement, facilitating ease of use.
Cons
- Limited to powder form, which may not appeal to those who prefer capsules or tablets.
- Some users may find the taste or texture undesirable when mixed solely with water.
Swanson L-Citrulline Malate offers a robust solution for those seeking to enhance their energy production and support healthy blood circulation. Each capsule delivers 750mg of L-Citrulline Malate, an amino acid that plays a vital role in both the Krebs and urea cycles of metabolism.
This dual action promotes not only energy production but also aids in the removal of metabolic waste products, making it a valuable supplement for overall wellness.
Pros
- Each capsule contains a potent 750mg dose of L-Citrulline Malate, supporting energy production and efficient removal of metabolic waste.
- Helps maintain healthy blood circulation, which can benefit overall cardiovascular health.
- Capsules are easy to swallow, making daily intake convenient for users.
Cons
- The supplement may cause minor side effects like stomach discomfort or bloating in some users.
- The large capsule size may be difficult for some individuals to swallow.
- Users looking for higher doses might need to take multiple capsules, which can be less convenient.
Final Thoughts
Among the various brands of L-Citrulline supplements reviewed, the Kaged Muscle Citrulline Powder is one of the best L-citrulline supplements available. This exceptional supplement offers a pure, plant-based form of L-citrulline, ensuring maximum effectiveness in enhancing muscle pumps, vascularity, and nitric oxide production.
What sets Kaged Muscle Citrulline apart is its unwavering commitment to quality and potency. This supplement guarantees optimal results for individuals seeking improved blood flow, nutrient delivery, and muscle recovery by providing a full dose of pure L-Citrulline rather than the less effective L-Citrulline malate. Its vegan-friendly formulation and absence of additives or fillers make it a trustworthy choice for health-conscious individuals.
Invest in this top-tier supplement today and experience the transformative power of enhanced nitric oxide synthesis, unparalleled muscle pumps, and accelerated recovery. Elevate your full potential with the best L-Citrulline supplement.
FAQs About L-Citrulline Supplements
How should I integrate L-Citrulline into my routine?
For best results, L-Citrulline should be taken 30-45 minutes before exercise to enhance nitric oxide production. On non-workout days, a smaller dose can help recover and maintain elevated nitric oxide levels.
Can I get enough L-Citrulline from eating watermelons?
While watermelons contain L-Citrulline, particularly in the rind, practical dietary intake is insufficient to match the dosages provided by supplements.
Who should avoid L-Citrulline supplementation?
Individuals with citrullinemia or similar metabolic disorders should avoid L-Citrulline, as it could exacerbate their condition.
Are there any side effects of taking L-Citrulline?
L-Citrulline is generally considered safe but can cause some mild side effects like stomach discomfort or lowered blood pressure, particularly at higher doses. It's advisable to start with a lower dose and gradually increase it.
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References
- US Preventive Services Task Force. (2021). Screening for hypertension in adults: US Preventive Services Task Force reaffirmation recommendation statement. JAMA, 325(16), 1650-1656. https://doi.org/10.1001/jama.2021.4987
- Divito, B., McLaughlin, M., & Jacobs, I. (2021). The effects of L-citrulline on blood-lactate removal kinetics following maximal-effort exercise. Journal of Dietary Supplements, 19(6), 704-716. https://doi.org/10.1080/19390211.2021.1926392
- Allerton, T. D., Proctor, D. N., Stephens, J. M., Dugas, T. R., Spielmann, G., & Irving, B. A. (2018). l-Citrulline supplementation: Impact on cardiometabolic health. Nutrients, 10(7), 921. https://doi.org/10.3390/nu10070921
- Gonzales, J. U., Raymond, A., Ashley, J., & Kim, Y. (2017). Does L-citrulline supplementation improve exercise blood flow in older adults? Experimental Physiology, 102(12), 1661–1671. https://doi.org/10.1113/EP086587
- Mirenayat, M. S., Moradi, S., Mohammadi, H., & Rouhani, M. H. (2018). Effect of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis of clinical trials. Current Hypertension Reports, 20(11), 98. https://doi.org/10.1007/s11906-018-0898-3
- Barkhidarian, B., Khorshidi, M., Shab-Bidar, S., & Hashemi, B. (2019). Effects of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis. Avicenna Journal of Phytomedicine, 9(1), 10–20. https://doi.org/10.22038/ajp.2019.12010