Top 8 Best Methylfolate Supplements

There has been a lot of hype about methylfolate supplements in the recent past, particularly because people with specified genetic differences may benefit from it greatly. This is a form of folate – a member of the B group of vitamins, which is involved in a number of processes in the body; in DNA manufacture and repair, in the creation of red blood cells and in proper functioning of nerves.

Folate is available in some foods and can be bought over the counter however due to the genetic variation some people are unable to convert it to the active form. This can eventually result in a deficiency that is called methylfolate, and this deficiency has been associated with conditions such as depression, anxiety, and cardiovascular diseases.

In the market, methylfolate supplements are available in tablets, capsules, and even powders forms. In this article, we will take you through the basics of choosing the right methylfolate supplement These include the dosage, form and the quality of the methylfolate supplement.

The amount of methylfolate that is required differs in the human body, and the wrong dosage may also elicit negative impacts. It is also important to decide on the form of the supplement that is easy to take and which the body can assimilate easily such as, capsules or tablets. Purity is another dimension that you will need to observe to get only the best supplements, as there are some supplements that are known to contain fillers or additives that are not healthy for human consumption.

Top 3 Best Methylfolate Supplements

1. Nutricost Methylfolate 1000mcg
2. One Elevated Methylfolate Supplement
3. Life Extension Optimized Folate (L-Methylfolate)

To make the selection of the best methylfolate supplements we conducted an experiment and analyzed the most popular products on Amazon. These food supplement can provide a direct source of bioavailable folate that the human body can immediately use. In this piece, we are going to be discussing more of some of the best methylfolate supplements that you can incorporate into your lifestyle to improve on your health.

In our quest for a premium methylfolate supplement, Nutricost Methylfolate 1000mcg is definitely one of the best.

Pros

• Delivers a potent dose of 1000mcg of methylfolate per capsule
• Gluten-free, non-GMO, and made without common allergens
• Suitable for vegetarians
• Supports overall mental and physical well-being

Cons

• Capsules might be a bit large for some
• Higher dosage might not be necessary for everyone
• May cause mild digestive discomfort in sensitive individuals

It has been a few weeks since we started using Nutricost Methylfolate and there appears to be an increase in our energy levels and focus. The dosage provided at 1000mcg is very high and is well appreciated especially in the mornings when one needs that extra boost. It is also gluten-free, non-GMO and does not contain any of the eight major allergens, which makes it a good option for people with special dietary needs.

On the negative side, the capsules are relatively large, which may be inconvenient for people with issues regarding taking pills. Furthermore, it should be noted that the high dosage may not always be required depending on the individual and can cause mild gastrointestinal discomfort in some users.

For a premium methylfolate product, try using the One Elevated Methylfolate Supplement.

Pros

• Lab tested and most powerful Methylfolate supplying essential support for DNA and neurotransmitter synthesis along with amino acid metabolism.
• Developed as most optimally absorbed and bioavailable 5-MTHF.
• Suitable for people who are diagnosed with MTHFR mutation.

Cons

• May cause allergic reactions in some people.
• Some users have reported difficulty swallowing the pills.
• Not suitable for vegans or vegetarians.

For several months, we have been using this supplement, and we have seen a dramatic increase in our overall health and energy. It works in DNA synthesis, neurotransmitter synthesis, and amino acid metabolism as the active form and the strongest Methylfolate that has been tested in laboratories. We acknowledge it has been formulated as most optimally assimilated and bioavailable 5-MTHF as to guarantee our bodies to utilize it appropriately.

One Elevated Methylfolate Supplement gives vital nutrients to support the brain, heart, nerves, and provide pregnancy and general population aid. MTHFR gene mutation is a type of condition that does affect how the body handles folate and therefore this book is good for those who have been tested positive to have MTHFR gene mutation.

For the purity and safety needs of One Elevated Methylfolate Supplement, the Supplement is produced in a fully GMP certified facility. To ensure that the formulated product is wholly free from contaminants from other batches, the product undergoes third-party testing. Making sure all products manufactured are Made in the USA.

Taking into account all the mentioned prospects and properties, we can confidently recommend the One Elevated Methylfolate Supplement for catalyst as a high-quality and effective methylfolate with the key supplementation for the brain activity, heart, and nerves.

If you want to stay healthy and improve your cognitive performance, then L-Methylfolate is best seen in the product of Life Extension Optimized Folate.

Pros

• Provides 1700 mcg of folate in the form of 5-MTHF, which is up to 7 times more bioavailable than ordinary folic acid.
• Helps maintain normal levels of homocysteine, a metabolic byproduct associated with heart and brain health.
• Manufactured in the USA using only the finest raw ingredients with the purity and potency your body deserves.

Cons

• Some people may find the price to be a bit high compared to other methylfolate supplements on the market.
• The tablets may be a bit difficult to swallow for some individuals.
• May not be suitable for individuals with certain medical conditions or who are taking certain medications.

We have been using the Life Extension Optimized Folate (L-Methylfolate) for several months now, and we feel a lot better as compared to before. It was also nice to know that the tablets are vegetarian and free from gluten while being easy to take altogether.

Another thing we appreciated about this supplement is that it delivers biologically active folic acid in the form of 5-MTHF which is more available by a mutation than the folic acid in ordinary supplementations. This makes those found in food more bio-available and friendly to our bodies, thus contributing to the health of both our heart and brain by promoting the use of the folate.

Other advantages of this supplement are that it assists in the control of homocysteine, which is metabolic byproducts that work with regards to heart and brains. That is why it is quite nice to know that this supplement helps to maintain proper levels of this useful cardiovascular marker.

Somewhere is highly recommend the Life Extension Optimized Folate (L-Methylfolate) to anyone who is interested in getting the best methylfolate supplement as what supports cardiovascular and cognitive well-being.

Among the best methylfolate supplements, Thorne 5-MTHF 1mg supplement is a perfect fit if you want only high-quality product.

Pros

• Provides nutritional cofactors for optimal homocysteine metabolism, supporting cardiovascular health
• Supports healthy blood vessel and nerve function
• Trusted brand chosen by champions and trusted by over 100 pro teams

Cons

• Relatively expensive compared to other methylfolate supplements on the market
• May cause initial side effects such as fatigue or nausea
• Some customers have reported issues with the safety seal on the bottle

Thorne 5-MTHF 1mg has become our favorite product for the past few of months and it does help upgrade our health status. The supplement is actually active folate, which is instituted for proper methylation, and it also enhances the mental HA approach. Such common features as choosing the brand by professional athletes, cooperation with Mayo Clinic under the health improvement and knowledge production, are also recognizable.

One of the primary disadvantages of this supplement is that its prices slightly on the higher side compared to other methylfolate supplements. On the same note, some customers have complained about difficulties with the safety seal s on the bottle which can be unsafe. Last but not least, special mention should be paid to the fact that some of the patients using this supplement may feel some adverse effects during the first days of taking this product, namely fatigue or nausea.

In sum, we strongly endorse Thorne 5-MTHF 1mg supplement for all those individuals who are in need of the top-quality methylfolate, with focus on cardiovascular, nerve health, and methylation.

If somebody would like to buy a methylfolate supplement there is no doubt that Thorne 5-MTHF 5mg is worth purchasing.

Pros

• Supports healthy methylation
• Boosts positivity and healthy outlook
• Supports healthy blood vessel and nerve function

Cons

• May not be suitable for everyone, especially those with certain medical conditions
• Some users may experience mild side effects like headaches or stomach upset
• Slightly more expensive than other methylfolate supplements on the market

Lately we have been using Thorne 5-MTHF 5mg of late and after a few weeks now, there is a great improvement in mood and energy respectively. The supplement comes in a form that can be consumed in small doses and there are no side effects that are bad for health.

Some of the conveniences that we have noted with this product include the fact that Thorne 5-MTHF 5mg is a product that promotes healthy methylation, which is a critical cofactor for a number of metabolic processes. It also helps in increasing positivity and maintain healthy blood vessel and nerve tissues of body.

As much as Thorne 5-MTHF may be unsuitable for particular user with other health complications, it is a good supplement of methylfolate for any person who wants to enhance their diets. While it may be a mere dollar or two more per month than other online trading platforms, it has features that warrant the extra cost.

To sum up, Thorne 5-MTHF 5mg seems to be an optimal option for folks who are searching for an efficient methylfolate supplement.

Specifically, we refer to Metabolic Maintenance L-Methylfolate 10mg as the best option for a premium methylfolate capsule.

Pros

• Taking methylated b vitamins such as l- methylfolate can support direct vitamin absorption.
• It is the only form of folate to cross the blood-brain-barrier.
• Necessary for the production of the neurotransmitters serotonin, norepinephrine, and dopamine, as well as overall nerve and cardiovascular maintenance.

Cons

• The price point is higher than some other methylfolate supplements on the market.
• Some users may experience gastrointestinal discomfort if taken on an empty stomach.
• The recommended dose is one capsule per day, which may not be enough for some individuals.

All in all, we are satisfied with the efficacy and quality of Metabolic Maintenance L-Methylfolate 10mg. For this reason, we regard Pure Papaya as a very potent product that does not contain any fillers, binders, preservatives, artificial colors or flavors. It is also as leveled as gluten free, egg free, peanut free, tree-nut free and contains no magnesium stearate. We turn to Metabolic Maintenance as a physician trusted source of physician quality phytonutrient supplements since 1984.

Studying this particular supplement has shown us it assisting in improving mood, ability to focus, and general health. We understand that is a better natural accessibility of folate b group of vitamins and is in fact the only form of folate that has capability to penetrate blood-brain barrier. As far as the side effects are concerned we have not had any problems after the intake of this supplement; albeit, some people might have some stomach upsets if they take it on an empty stomach.

All things considered, Metabolic Maintenance L-Methylfolate 10mg is definitely worthy of recommendation for individuals who prefer products of superior quality that are likely to positively influence the functionality of the brain, promoting better mood and cognition as a result.

For those interested in an effective Methyl Folate supplement, the Horbäach Methyl Folate is one that could be considered.

Pros

• This supplement is derived from high-quality sourcing standards and is expertly crafted.
• It is a convenient form of Methyl Folate, with each quick-release capsule delivering 1000mcg of the nutrient.
• Horbäach's Methyl Folate is Non-GMO and Gluten-Free, making it a safe choice for many people.

Cons

• Large quantities of L-Methyl folate may mask the effects of pernicious anemia and Vitamin B-12 deficiency, so it's important to consult with your doctor before use.
• If any adverse reactions occur, immediately stop using this product and consult your doctor.
• The bottle is not air-tight, so you may want to transfer the capsules to a different container if your house isn't climate controlled.

It has been around several weeks now since we started using Horbäach’s Methyl Folate and we have realized the different our energy levels and general health are. These are palatable, small round shaped and light easy to swallow capsules having either somewhat or no flavor and smell at all.

Before taking Methyl Folate, you need to know that it should be taken with a proper prescription since it could cause side effects if you have certain health conditions or if you are undergoing a treatment with other medications. But if you’re seeking for a perfect and easy method to enrich their diet with this crucial vitamin, then Horbäach’s Methyl Folate will be perfect.

For those in the market for a good methylfolate supplement, the MethylPro L-Methylfolate 15 mg – 90 Capsules are a great option.

Pros

• This supplement contains active methylfolate, which is the most advanced form for better results.
• With its professional strength folate capsules, MethylPro offers a range of potent therapeutic doses depending on your personal goals.
• L- methylfolate may support heart & brain health by promoting already healthy peripheral nerve function and nitric oxide production.

Cons

• This supplement is quite expensive compared to other methylfolate supplements on the market.
• Some users may experience mild side effects such as headaches or nausea.
• It is important to take this supplement only as directed under the supervision of a Physician.

I am a health-conscious person who buys MethylPro L-Methylfolate 15 mg – 90 Capsules and as far as my few weeks experience is concerned, there has been a noticeable positive change in my mood and energy levels. This supplement comes in a small capsule form and is very easy to swallow and does not include any binders, soy, casein, dairy products or eggs, wheat or nuts.

As one of the features, we like the fact that this kind of folic acid is the only one that can pass through the blood-brain barrier and that makes it useful for maintaining the health of brain. Also important to note is the absence of fillers or binders, which are usually added to make the supplement easier to manufacture, but only dilute the product and its benefits; in this case, the methylfolate being administered is powerful and undiluted.

We would also like to stress that, despite the fact that this supplement is really costly in comparison with other similar products, it is worth each penny because product quality and efficiency of this product is truly impressive. For a quality supplement that can enhance our health and well-being, you should consider MethylPro L-Methylfolate 15 mg - 90 Capsules.

Buying Guide

As discussed earlier, available methyl folate supplements in the market varies in terms of formulation, dosage and ingredients added and therefore to ensure you get the right products consider the following tips.

Dosage

The first thing that you must look into is the dosage of the supplement that you are planning to use. The available forms of methylfolate include methylfolate supplements in different quantities, such as 400mcg to 5mg or higher strengths. The ideal dosage should therefore be determined based on the user’s requirements, as using a higher amount has been found to cause some undesired impacts. As with any other dietary supplement, we would advise you to speak to your healthcare provider regarding the particular dosage that may be suitable for your needs.

Form

There are different types of methylfolate present in the market such as tablets, capsules and powders. The form that you take may be something that this is more of a personal choice but depending on the dietary plan that you take at the moment. For instance, if you are an agent that relies on consuming vegan products, then you could try selecting a capsule or your powder form that is vegan.

Quality

In the case of supplements, however, it is very important to focus on quality. Search for a product that is produced by a reputable company and which has gone through quality testing from an outside source to ensure that they contain the right type of ingredients as recommended. You may also want to select a product that has been endorsed by a third-party organization like the (NSF International or USP) to help you get a product of high quality.

Price

However, this varies and is not a major determinative factor to consider when choosing a methylfolate supplement since there are cheap brands and expensive ones in the market. Granular clarification before proceeding with actually buying the product is that the expensive product may not necessarily be better than a cheaper one hence conducting research on the prices.

Other Considerations

Other points related to the above-mentioned factors that need to be taken into consideration while purchasing a methylfolate supplement include: For instance, you may have a preference for a product which is naturally not contain certain ingredients that most people are intolerant of like gluten, soy and dairy. You may also need to look for a product that also has other healthy additives that include vitamin B12 or magnesium among others.

In summary, one has to be very cautious in selecting the most suitable methylfolate supplement for the desired application with special regard to the dosage, form, quality, price, etc. Therefore, it is always advisable to first research about the product and consult a healthcare professional so as to identify one that will complement your health and fitness.

Frequently Asked Questions

What is the recommended dosage of methylfolate for MTHFR?

It’s recommended that anyone with MTHFR should take methylfolate and the dosage may be different depending on an individual. However, in order to ascertain that you will get the right dosage, it is advisable that you consult a healthcare provider.

What are the benefits of taking a 5-MTHF supplement?

The 5-MTHF formula can assist in the enhancement of the methylation process, which is relevant to DNA replication, synthesis of neurotransmission, and numerous other metabolic processes in the body. Before giving birth, the maternal food may also aid the development of a healthy fetus.

What are the differences between 5-MTHF and folic acid supplements?

5-MTHF is the biologically active form of the Vitamin, as folic acid that is consumed needs to be metabolized to become 5-MTHF for the body to use. While some people are able to methylate folic acid to form 5-MTHF, others cannot readily do this easily and, therefore, it is better if they take 5-MTHF.

What are the best sources of folate in food?

In foods, folate can be found relatively well in green leafy vegetables and in beans, lentils, avocado and fortified cereals. However, some individuals may struggle in terms of letting their body absorb folate from natural products, and therefore, a supplement would be more ideal.

What are the benefits of taking a methylfolate supplement?

Methylfolate supplements aim at supporting the healthy production of methylation and help provide the required amounts of folate that the body may have trouble assimilating from foods. It may also help sustain a healthy pregnancy to the extend of fetal development.

Are all methylfolate supplements the same quality?

It should be noted that not all methylfolate products in the market are the same. In order to reap the benefits noted above and avoid adverse effects, it is crucial to take a supplement of good quality from a reputable dealer. In this regard, opt for supplements that have been tested by a third party on their quality and on whether they contain impurities.