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Top Treatments for Menopause

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Written by Andrew Le, MD.
Medically reviewed by
Last updated June 12, 2024

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Menopause is a natural biological process that marks the end of a woman's reproductive years. During this transition, women may have a range of physical and emotional symptoms that can impact their quality of life. How severe and long symptoms last can vary greatly among women. Fortunately, there are many treatment options to help manage these symptoms and improve overall well-being.

Menopause typically occurs between the ages of 45 and 55, with the average age being 51. However, some women may reach menopause earlier or later than this range. The transition to menopause, known as perimenopause, can last several years and causes fluctuating hormone levels and irregular menstrual cycles. Once a woman has gone 12 consecutive months without a menstrual period, she is considered to be in menopause.

Some of the most common symptoms include hot flashes, night sweats, vaginal dryness, mood changes, poor sleep, and weight gain. These symptoms are caused by the decline in estrogen levels that occurs during menopause. While some women may get only mild symptoms, others may find them severe enough to interfere with daily life and overall well-being.

This article explores the top treatments for menopause, including hormonal therapies, non-hormonal medications, lifestyle changes, alternative and complementary therapies, and other strategies for managing symptoms.

Hormonal Treatments for Menopause

Hormonal medications are the most effective treatments for managing menopausal symptoms, particularly hot flashes and night sweats. The two main types of hormonal therapy are:

  1. Estrogen Therapy (ET): This contains only estrogen, and is typically prescribed for women who have had their uterus removed through hysterectomy.
  2. Estrogen-Progestin Therapy (EPT): This combination therapy is prescribed for women who still have their uterus, as the progestin helps to protect against endometrial cancer.

Hormonal treatments have been shown to effectively reduce the frequency and severity of hot flashes, improve vaginal dryness and sexual function, and protect against bone loss.

However, they may carry some risks in women who have certain conditions, like breast cancer, stroke, and blood clots. It's important to discuss the potential benefits and risks of hormonal therapy with your healthcare provider to determine if it is the right choice for you.

Available forms of hormonal treatments

Hormonal treatments for menopause are available in various forms, including:

  1. Oral medications: Estrogen and progestin can be taken as pills, either separately or in combination.
  2. Transdermal patches: These patches deliver estrogen and/or progestin through the skin and are changed every few days.
  3. Vaginal creams, rings, or tablets: These low-dose estrogen products are used to treat vaginal dryness and discomfort.
  4. Injectable estrogen: This form of estrogen is administered by injection and is sometimes used for women who have difficulty absorbing oral medications.

The type and dose of hormonal treatment will depend on a woman's individual needs and medical history. Women should work closely with their healthcare provider to decide on the most appropriate option for their situation.

Non-Hormonal Treatments for Menopause

For women who cannot or choose not to use hormonal therapy, there are several non-hormonal treatment options available. These include:

  1. Antidepressants: Certain antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), have been shown to reduce hot flashes and improve mood in menopausal women.
  2. Gabapentin: This anti-seizure medication has been found to be effective in reducing hot flashes.
  3. Clonidine: This blood pressure medication may help to reduce hot flashes, although its effectiveness is generally lower than that of hormonal therapy or antidepressants.
  4. Ospemifene: A selective estrogen receptor modulator (SERM) that can help relieve vaginal dryness and painful intercourse.
  5. Cognitive-behavioral therapy (CBT): A type of therapy that can help you cope with hot flashes and poor sleep.

There are also over-the-counter options that may help with menopausal symptoms. However, it's important to note that the effectiveness and safety of these products can vary. Always, talk with your healthcare provider before starting any new medication or supplement.

OTC products include:

Lifestyle Changes for Menopause Management

Making healthy lifestyle changes can go a long way in helping to manage menopausal symptoms and promote overall well-being. Some key lifestyle modifications include:

  1. Eating a balanced diet: A diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats can provide the nutrients needed to support bone health, maintain a healthy weight, and reduce the risk of chronic diseases.
  2. Exercising regularly: Engaging in regular physical activity, such as brisk walking, swimming, or strength training, can help to reduce hot flashes, improve mood and sleep, and maintain bone and muscle mass.
  3. Maintaining a healthy weight: Carrying excess weight can exacerbate menopausal symptoms like hot flashes and mood changes. Adopting a balanced diet and doing regular exercise can help maintain a healthy weight.
  4. Managing stress: Practicing stress-reduction techniques such as deep breathing, meditation, or yoga can help to alleviate mood swings, anxiety, and sleep disturbances.
  5. Staying cool: Dressing in layers, keeping a fan nearby, and avoiding triggers like spicy foods or hot beverages can help to minimize hot flashes.
  6. Quitting smoking: Smoking can worsen hot flashes and increase the risk of osteoporosis and heart disease, so quitting is an important step in managing menopausal symptoms and protecting overall health.
  7. Staying hydrated: Drinking plenty of water and avoiding excessive caffeine and alcohol can help hot flashes, headaches, and fatigue associated with menopause.

Alternative and Complementary Therapies for Menopause

Many women find relief from menopausal symptoms through alternative and complementary therapies. Some popular options include:

  1. Herbal supplements: Black cohosh, red clover, and evening primrose oil are among the most commonly used herbs for managing menopausal symptoms, particularly hot flashes. However, the evidence for their effectiveness is mixed, and they can interact with other medications, so it's important to talk with a healthcare provider before trying them..
  2. Acupuncture: Some studies suggest that acupuncture may help reduce hot flashes and improve sleep and mood in menopausal women, although more research is needed to confirm its effectiveness.
  3. Mind-body practices: Techniques such as mindfulness meditation, yoga, and tai chi can help to reduce stress, improve mood, and promote relaxation, which may in turn help to alleviate menopausal symptoms.
  4. Bioidentical hormone therapy: This controversial approach involves the use of custom-compounded hormones that are chemically identical to those produced by the body. While proponents claim that bioidentical hormones are safer and more effective than conventional hormone therapy, there is limited scientific evidence to support these claims, and the FDA does not regulate these products for safety or efficacy.
  5. Massage therapy: Massage can help to reduce stress, promote relaxation, and alleviate muscle tension and pain that may be associated with menopause.
  6. Aromatherapy: Certain essential oils, such as lavender and peppermint, may help to reduce hot flashes and promote relaxation when used in a diffuser or applied topically.
  7. Hypnosis: Some studies suggest that hypnosis may be effective in reducing hot flashes and improving sleep in menopausal women.
  8. Homeopathy: This alternative medicine system uses highly diluted substances to stimulate the body's natural healing processes. Some women find relief from menopausal symptoms with homeopathic remedies, although scientific evidence for their effectiveness is limited.

Managing Specific Symptoms of Menopause

While hot flashes and night sweats are the most well-known symptoms of menopause, other symptoms related to the dip in hormones may happen during this time. Here are some strategies for managing specific menopausal symptoms:

  1. Vaginal dryness and discomfort: Using a vaginal moisturizer or lubricant, or considering vaginal estrogen therapy, can help reduce dryness, itching, and pain during intercourse.
  2. Urinary tract symptoms: Practicing pelvic floor exercises, using vaginal estrogen therapy, and maintaining good hygiene can help prevent and manage urinary incontinence and recurrent urinary tract infections.
  3. Sleep disturbances: Establishing a regular sleep schedule, creating a cool and comfortable sleep environment, and practicing relaxation techniques can help to improve sleep quality and combat insomnia.
  4. Mood changes: Doing regular exercise, practicing stress-reduction techniques, and seeking support from friends, family, or a mental health professional can help with mood swings, irritability, and depression.
  5. Memory and concentration issues: Staying mentally active, getting enough sleep, and managing stress can help cognitive function and reduce menopause-related "brain fog."

Conclusion

Menopause can cause a range of physical and emotional symptoms. But with the right treatments and strategies, women can reduce their symptoms. Hormonal treatments are the most effective therapies and have been sanctioned by major medical groups. They are generally safe for most women. There are other non-hormonal treatments and lifestyle strategies that can also help prevent and relieve symptoms.

Citations:

Here is a combined list of all complete citations from the reports:

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  2. National Institutes of Health. (2018). Menopause. https://www.nih.gov/health-information/menopause
  3. Mayo Clinic. (2021). Menopause: Diagnosis & treatment. https://www.mayoclinic.org/diseases-conditions/menopause/diagnosis-treatment/drc-20353401
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Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
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