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Sleep Problems in Your 30s May Affect Your Cognitive Health by Midlife: New Study Warns

Sleep Problems in Your 30s
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Written by Andrew Le, MD.
Medically reviewed by
Last updated May 21, 2024

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A new investigation has revealed that sleep disturbances experienced during one's mid-30s to late 40s may have significant implications for cognitive function by midlife. The study, "Association Between Sleep Quantity and Quality in Early Adulthood With Cognitive Function in Midlife," published in the journal Neurology, suggests that the quality of sleep could greatly influence cognitive health, more than the duration of sleep itself.

The study builds upon burgeoning evidence that poor sleep quality may heighten the risk of dementia. Black and White adults in their midlife were the focus of the research led by Yue Leng, PhD, and colleagues from the University of California, San Francisco. The research used wrist actigraphy, an objective measurement of sleep patterns, to gauge both sleep duration and quality. An array of cognitive tests was then performed approximately 11 years later to assess each participant's cognitive performance.

Key findings, derived from a group comprising 58% women and 44% Black individuals, reveal that participants displaying the highest levels of sleep fragmentation had over twice the likelihood of experiencing poorer cognitive performance in tasks assessing executive function and global cognition compared to those with lower levels. Notably, this association did not vary by race or sex. However, neither subjective sleep quality nor sleep duration on their own exhibited a direct link with cognitive function in midlife.

The implications of these results are significant. The authors emphasize the importance of sleep quality in maintaining cognitive health, suggesting even in midlife, sleep might play a substantial role in shaping our cognitive future. Furthermore, the study champions objective measures over subjective self-reporting to achieve a clearer picture of the relationship between sleep and cognitive performance.

The research comes with notable strengths, including the objective assessment of sleep and the diverse demographic, but it also has limitations, such as the lack of more detailed sleep disorder measures like polysomnography. Nonetheless, the findings underscore the crucial need for a life course approach to examining modifiable risk factors for cognitive aging.

In conclusion, this study posits that fragmented sleep in early midlife could be an important marker for cognitive health concerns later on, highlighting a potentially modifiable risk factor for clinicians and public health professionals to consider. For those interested in learning more, the full article by Dr. Yue Leng and colleagues is accessible through the journal Neurology.

This summary of the research was made possible with the assistance of Buoy Health.

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Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
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References

Leng, Y., Knutson, K., Carnethon, M. R., & Yaffe, K. (2024). Association Between Sleep Quantity and Quality in Early Adulthood With Cognitive Function in Midlife. Neurology, 102, e208056. https://doi.org/10.1212/WNL.0000000000208056