How to Get Semaglutide for Weight Loss: A Comprehensive Guide
UpdatedOctober 23, 2024
Semaglutide is one of five medications endorsed by the FDA for weight loss. These medications, including orlistat, phentermine/topiramate, naltrexone/bupropion, and liraglutide, are recommended with a reduced-calorie diet and increased physical activity.
To find out how to get Semaglutide, note that Semaglutide is administered as a once-weekly, subcutaneous injection at a dose of 2.4 mg, offering a solution for chronic weight management. People using semaglutide lost an average of 12.7 kg more weight than those on a placebo.
The impressive weight loss effects of semaglutide have caught the attention of scientists, doctors, and the public, making people excited to learn more. In this article, we'll discuss what semaglutide is, how it helps with weight loss, how well it works, any possible side effects, and how you can get it.
So, let’s get started.
🔑 Key Takeaways
- Semaglutide primarily reduces appetite, resulting in prolonged satiety.
- On average, expect a weight loss of approximately 15%, equating to 1 to 3 pounds per week.
- Semaglutide demonstrates substantial weight loss benefits for non-diabetic obese individuals.
- Individuals with a history of medullary thyroid cancer should avoid semaglutide.
- The FDA advises obtaining semaglutide from licensed healthcare providers.
What is Semaglutide?
Semaglutide is a medication categorized under glucagon-like peptide-1 receptor agonists (GLP-1 RAs). This class of medications mirrors the function of the GLP-1 hormone, which the gut produces after eating. The GLP-1 hormone has several critical roles:
KORB offers semaglutide program
KORB offers semaglutide program
We partnered with KORB Health to offer an easy telemedicine and pharmacy solution that brings effective GLP-1 agonists (semaglutide) straight to your door.
💡 Did You Know?
The GLP-1 hormone increases satiety by forming a gel in the intestines through water absorption. This hormone also reduces the appetite hormone ghrelin. Learn more by checking out our top 11 best fat burners for women.
- Blood Sugar Regulation: GLP-1 signals the body to produce more insulin, reducing blood glucose levels. This property of GLP-1 has made semaglutide a prevalent choice for treating Type 2 diabetes for over 15 years.
- Appetite Suppression: Higher concentrations of GLP-1 interact with the brain's areas responsible for suppressing appetite and indicating satiety. This means using semaglutide alongside proper diet and exercise can result in substantial weight loss.
- Fat-Burning Mode Activation: Semaglutide has the capability to keep the body in a "fat-burning" mode. Since it targets fat cells and regulates blood sugar, users won't experience muscle mass loss or dehydration, often associated with other weight loss methods.
- Plaque Production Inhibition: Research has shown that semaglutide can impede plaque formation in blood vessels.
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How Does Semaglutide Aid in Weight Loss?
When incorporated into a structured weight loss program, semaglutide offers multiple benefits:
- Appetite Reduction: One of the primary effects of semaglutide is appetite reduction, making users feel fuller for extended periods. This naturally leads to a decrease in food intake.
- No Strict Dietary Restrictions: While no stringent food restrictions are associated with the semaglutide program, a nutritious diet is advised. A balanced diet, rich in proteins and nutrient-dense foods, tends to enhance feelings of well-being and energy levels.
- Optional Exercise: Physical activity is recommended but not mandatory. Even simple activities like walking can provide significant health benefits for those unaccustomed to regular exercise.
- Physical and Mental Health Coaching: A distinctive aspect of the semaglutide weight loss program is the availability of a virtual health coach. Besides guiding users on healthier eating plans, these coaches provide essential support in tackling emotional and psychological triggers for overeating, such as boredom, sadness, or anger.
- Holistic Health Approach: Recognizing that optimal health involves the mind, body, and soul, the program emphasizes a holistic approach. The aim is to equip users with tools to make healthier lifestyle choices after the program ends.
- Expected Weight Loss: On average, individuals can anticipate a weight loss of around 15%, translating to a typical range of 1 to 3 pounds weekly. This rate can fluctuate based on the individual's initial weight.
What Is The Science Behind GLP-1 And Weight Loss?
GLP-1 is an incretin hormone integral to appetite control and digestion. After consuming a meal, your digestive system releases incretin hormones. These hormones help reduce blood sugar levels by:
- Stimulating insulin release
- Blocking sugar production
- Slowing down the speed at which food exits the stomach (gastric emptying)
This culmination of actions gives a sensation of fullness, thereby reducing appetite and aiding in weight loss. Medications like semaglutide that produce these effects are termed "incretin mimetics."
Though GLP-1 agonists, such as semaglutide, the resultant weight loss benefit has also been recognized as beneficial for non-diabetics.
Is Semaglutide Effective For Weight Loss In Non-Diabetics?
Yes, semaglutide has proven to promote significant weight loss in non-diabetic obese individuals. In a study, participants using semaglutide lost up to 20% of their weight in 68 weeks, compared to just 2.4% with only lifestyle changes.
Furthermore, a systematic review found semaglutide reduced weight by an average of 10.09% and improved cardiovascular health indicators. While there are side effects like nausea and diarrhea, they are typically mild and transient.
Semaglutide for Type 2 Diabetes Management
While semaglutide has gained popularity for weight loss, it's important to note its significant benefits for people with type 2 diabetes. Originally approved to treat type 2 diabetes, semaglutide helps lower blood sugar levels by mimicking a hormone called GLP-1, which stimulates insulin production. For individuals with diabetes, semaglutide offers a dual advantage: improved glycemic control and potential weight loss.
Research has shown that semaglutide can be highly effective in managing type 2 diabetes. It not only helps regulate blood sugar but also promotes weight loss, which is crucial for many people with diabetes. Even a modest weight reduction of 5-10% can lead to significant improvements in insulin sensitivity and overall diabetes management. In some cases, substantial weight loss achieved through semaglutide use, combined with lifestyle changes, may even lead to diabetes remission for some individuals.
However, it's essential to understand that semaglutide is not a standalone solution for diabetes management. It works best when used in conjunction with a healthy diet, regular exercise, and other diabetes medications as prescribed by a healthcare provider. For people with type 2 diabetes considering semaglutide, it's crucial to work closely with their medical team to monitor blood sugar levels, adjust medications as needed, and address any potential side effects.
Semaglutide is a promising weight management medication for non-diabetic obese patients, enhancing overall health and quality of life.
What Is The Approval And Clinical Evidence For Semaglutide?
Wegovy is the exclusive semaglutide medication that has received weight management approval from the US-FDA. It is essential to underscore that results from semaglutide-based weight loss will differ based on several factors, including individual lifestyle choices.
▶️ Watch:
Wegovy, the latest weight loss drug from Novo Nordisk, aids obese individuals, managing chronic weight and related conditions like hypertension, hyperlipidemia, and diabetes. Watch the video for details:
WEGOVY: What You Didn’t Know! Endocrinologist Explains
What are the side effects of Semaglutide injections?
Semaglutide injections are usually well-tolerated by most people. However, some individuals might experience side effects. Gastrointestinal issues are among the most common complaints, especially among those who have just started using the drug. The typical side effects can include:
- Gastrointestinal Issues: Nausea, diarrhea, constipation, and gassiness are commonly reported. These digestive complaints often manifest when first starting the medication.
- Dizziness: Some people might feel light-headed or dizzy.
- Fatigue: Tiredness or weariness is another possible side effect.
- Headaches: This can be another outcome of the medication.
- Stomach-Related Issues: Users might experience vomiting, stomach pain, bloat (distension), or indigestion.
While these side effects are typically mild compared to the complications associated with obesity, there are also more serious side effects. These include:
- Thyroid C-cell tumors: This has been observed in animal studies, although a direct connection in humans is yet to be confirmed. Due to this potential risk, semaglutide should not be taken by those with a personal or family history of certain thyroid tumors.
- Pancreatitis: Inflammation of the pancreas.
- Gallbladder disease: Also known as cholelithiasis.
- Kidney Damage: Known as acute kidney injury.
- Low Blood Sugar: Also called hypoglycemia.
- Allergic Reactions: Symptoms can include swelling of the face, tongue, or throat and difficulty in breathing.
- Eye Problems: Particularly for people with Type 2 diabetes.
- Fast Heart Rate: Increased heart rate.
- Mood Changes: There is a risk of suicidal thoughts and behaviors, as reported with other weight loss medications.
What Is The Dosage Of Semaglutide?
Semaglutide is typically administered as a once-weekly subcutaneous injection. The injection can be given in the abdomen, upper arm, or thigh. To prevent complications, users must rotate their injection site within the same body area each time. The dosage is usually increased progressively to make side effects more manageable. A typical dosing schedule is:
Month 1:
- Dosage (mg): 0.25
- Frequency: Once weekly
- Note: Initial dose
Month 2:
- Dosage (mg): 0.5
- Frequency: Once weekly
- Note: Increased dosage
Month 3:
- Dosage (mg): 1
- Frequency: Once weekly
- Note: Further dosage increase
Month 4:
- Dosage (mg): 1.7
- Frequency: Once weekly
- Note: Increment in dosage
Month 5 and Beyond:
- Dosage (mg): 2.4
- Frequency: Once weekly
- Note: Target maintenance dose
If a patient misses their dose and their next scheduled dose is more than 2 days away, they should take it as soon as possible. If the next dose is less than 2 days away, they should skip the missed dose and continue their schedule. Double dosing is discouraged.
🗒️ Health Note:
Patients are always advised to communicate with their healthcare provider regarding any side effects, dosing concerns, or related issues.
Who Should (And Should Not) Take Semaglutide For Weight Loss?
The US-FDA recommends taking Wegovy for weight loss if an individual meets either of the following conditions:
- Possesses a body mass index (BMI) of 27kg/m^2 or greater and at least one weight-related ailment such as high blood pressure, Type 2 diabetes, or high cholesterol.
- Has a BMI of 30kg/m^2 or higher.
However, semaglutide should be avoided if an individual has any of the following:
- A history of medullary thyroid cancer.
- A history of gallbladder disease.
- A history of pancreatitis.
- Multiple endocrine neoplasia syndrome type 2 (MEN2).
💡 Did You Know?
Endocrine multiple neoplasia (MEN1) is a rare inherited genetic disorder that makes individuals prone to various endocrine tumors. Among the primary tumors seen in MEN1 are growths in the parathyroid glands, pituitary glands such as prolactinomas, and the pancreas. Learn more by reading our article on Prolactinoma.
What Are The Costs And Shortages Updates For Semaglutide?
In the US, as of February 2023, a recommended monthly dose of semaglutide medication, like Ozempic, costs around $804. An average pre-filled pen of Ozempic, with a recommended weekly dosage of 0.5–1 milligram, is priced at approximately $195. Meanwhile, Wegovy is available for $1,349.02 per package.
As of June 7, 2023, three medications—Trulicity, Ozempic, and Wegovy—are facing shortages, as indicated by the US-FDA Drug Shortages list. The primary reason behind these shortages is a significant surge in demand.
Novo Nordisk, the manufacturer of Ozempic and Wegovy, is experiencing shortages due to this increased demand. Ozempic production has been reduced for certain doses and presentation types, while Wegovy also faces shortages across various dose strengths. Despite efforts to boost production, the supply is projected to fall short of demand.
In Australia, the availability of Ozempic is gradually improving. Still, it will continue to be listed as in shortage on the Therapeutic Goods Administration (TGA) Medicine Shortage Reports Database until December 31, 2023, due to high demand. Novo Nordisk anticipates a consistent supply in the future.
How Can You Get Semaglutide?
To obtain semaglutide for weight management, you must follow specific steps to ensure your safety and efficacy. Here is a summary of the process:
Consultation with Healthcare Provider
Schedule a visit with a licensed healthcare provider who will assess your health history and goals to determine if semaglutide is suitable for you. Telehealth appointments are an option, but some lab tests may require in-person visits.
Prescription and Pharmacy
The process is straightforward if you're wondering how to get a semaglutide prescription. If you qualify for semaglutide, your healthcare provider will prescribe the appropriate option. The prescription will be sent to a physical or online pharmacy. Inquire about home delivery options with your pharmacy.
KORB offers semaglutide program
KORB offers semaglutide program
We partnered with KORB Health to offer an easy telemedicine and pharmacy solution that brings effective GLP-1 agonists (semaglutide) straight to your door.
Insurance Coverage
On how to get semaglutide covered by insurance, you'll need to check your health insurance plan. Contact your health insurance company to confirm whether semaglutide prescriptions are covered
Getting Semaglutide without Insurance
If uninsured, you can explore patient assistance programs (PAP) provided by the drug manufacturer. Check the company's website to determine if you're eligible. If your insurance denies your claim, your healthcare provider can assist you in obtaining a coverage request letter.
FDA Recommendations
To ensure safety and effectiveness, the FDA recommends obtaining semaglutide only through:
- Licensed healthcare professionals
- State-licensed pharmacies
- FDA-registered outsourcing facilities
Beware of Unregulated Sources
When looking for information on how to get semaglutide online, it's crucial to exercise caution. Some products may not contain the approved active ingredient and could be unsafe. There's a risk of obtaining unregulated, untested forms of semaglutide. The FDA's BeSafeRx campaign guides safely accessing medication online.
In-Person Assessments
Even if you successfully obtain a prescription online, you'll likely need to undergo in-person laboratory tests or other assessments.
Remember that your health and safety should be a priority throughout this process. Always follow the guidance of licensed healthcare professionals and trusted sources when seeking medication.
Wrap-Up
Semaglutide, and knowing how to get it, has become a powerful way to manage weight and is highly regarded in the medical field. It works well for people with diabetes and those without, using multiple methods to help with weight loss.
As more people want to try semaglutide and supply issues are still being sorted out, it's important for individuals to follow the process and focus on their health carefully.
If you're looking for a good way to manage your weight comprehensively, Semaglutide could be a helpful option.
FAQs on Semaglutide for Weight Loss
Does semaglutide eliminate belly fat?
Semaglutide helps shed weight, including stubborn belly fat and boosts lean body mass. Progress in overall body composition is directly linked to the weight lost with semaglutide.
Is semaglutide weight loss permanent?
Semaglutide aids in weight loss, but weight tends to return after discontinuing its use. Fundamental strategies for managing obesity remain dietary and exercise changes.
How to get semaglutide without insurance?
Explore patient assistance programs, prescription discount cards, and government assistance, or consult your healthcare provider for alternative options.
Can you stop semaglutide?
Indeed, semaglutide leads to weight loss, but this effect reverses upon cessation. Research shows significant weight regain in participants one year after stopping semaglutide, with about two-thirds of prior weight loss regained.
Will weight return after stopping semaglutide?
A woman's experience post-semaglutide discontinuation reveals that significant weight loss is attainable with the medication, but upon stopping, patients commonly regain up to two-thirds of the lost weight.
Is weight loss achievable in the first month of semaglutide?
During semaglutide use, some notice results within eight weeks, while most observe changes within 12 weeks. Clinical trials indicate that participants on weekly semaglutide doses experienced an average body weight reduction of 5-10 percent.
How to get semaglutide?
To get semaglutide, you should consult a healthcare provider who can prescribe it based on your individual needs and circumstances.
Are there any specific requirements or steps for getting Semaglutide?
Yes, obtaining Semaglutide involves consulting with a healthcare professional who will assess your suitability for the medication and provide guidance on how to get semaglutide as part of your weight management plan.
References
- ashp
- Therapeutic Goods Administration
- Wilding JPH, Batterham RL, Calanna S, et al. Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine. 2021; 384(11):989-1002. https://www.nejm.org/doi/full/10.1056/NEJMoa2032183
- American Diabetes Association. Losing Weight & Diabetes. https://diabetes.org/health-wellness/weight-management
- Diabetes UK. Reversing type 2 diabetes. https://www.diabetes.org.uk/diabetes-the-basics/type-2-reverse