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Best Memory Supplements to Boost Cognitive Function

Written by Andrew Le, MD

UpdatedSeptember 5, 2024

Whether it's forgetting important appointments, struggling to recall names, or feeling mentally sluggish, these issues can significantly impact daily lives and overall productivity.

Studies show that up to 40% of people over the age of 65 experience some form of memory impairment, and even younger individuals are not immune to these challenges due to stress, poor diet, and lack of sleep. Additionally, cognitive decline can start as early as our 30s, making it crucial to address these issues before they worsen.

Fortunately, there's a way to improve this. This article will explore the best memory supplements that can help enhance cognitive function, reduce brain fog, and improve mental clarity. By incorporating these supplements into your daily routine, you can take proactive steps to support your brain health and sharpen your memory.

Common Ingredients in Memory Supplements

When choosing supplements for memory, it's important to look for ingredients that have been scientifically studied for their benefits to cognitive function and memory. Here are some of the best ingredients to look for:

1. Ginkgo Biloba

Ginkgo biloba is a type of tree native to China cultivated for thousands of years for various uses. It is well-known for its fan-shaped leaves and is often called "ginkgo."

According to animal studies, Ginkgo biloba improves memory by lowering the amount of harmful free radicals in the brain. It also helps prevent age-related changes in the hippocampus, which is involved in forming, organizing, and storing memories in the brain.

2. Bacopa Monnieri

Bacopa monnieri, often referred to as Brahmi, is a herb traditionally used in Ayurvedic medicine for hundreds of years. It originates from India and flourishes in wet, tropical regions. This plant is known for its potential cognitive-enhancing properties.

In a 12-week study involving 81 adults aged 55 and older, Bacopa monnieri significantly enhanced memory acquisition and retention in healthy older Australians. Additionally, a meta-analysis that included data from six studies lasting 12 weeks or longer showed that Bacopa monnieri improved memory-free recall, though it did not enhance other cognitive functions. These studies typically used a dose of 300 to 450 mg of Bacopa extract, standardized to contain 10 to 20% bacopa glycosides.

3. Omega-3 Fatty Acids

Omega-3 fatty acids are essential fats that your body needs but cannot produce on its own, so they must be obtained through diet. The primary types of omega-3 fatty acids are:

  • DHA (docosahexaenoic acid)
  • EPA (eicosapentaenoic acid)
  • ALA (alpha-linolenic acid)

A recent exploratory study discovered that in healthy older adults, higher levels of omega-3 fatty acids are linked to improved memory, faster processing speed, and better structural brain measurements.

These benefits are attributed to the positive effects of omega-3 fatty acids on synaptic membranes, their ability to protect neurons from damage and atrophy, and their overall support of brain health and function, particularly in subcortical regions like the hippocampus.

4. Phosphatidylserine

Phosphatidylserine is a phospholipid, which is a type of fat molecule that forms an essential part of cell membranes, especially within brain cells. It plays a key role in preserving cell structure and function and is important for cognitive functions.

Researchers investigated the effects of soybean-derived phosphatidylserine on cognitive function in elderly Japanese individuals with memory complaints. Participants with initially low neuropsychological test scores who took phosphatidylserine experienced significant memory improvements, particularly in delayed verbal recall.

5. Huperzine A (HupA)

Huperzine A is a naturally occurring compound extracted from the Chinese club moss plant, Huperzia serrata. A clinical study found that administering 200 mcg of Huperzine A twice a day resulted in significant improvements in memory, cognitive function, and behavioral factors in 58% of patients with Alzheimer's disease.

Another study mentioned that HupA stands out compared to other Alzheimer's drugs like tacrine, donepezil, and rivastigmine because it better penetrates the brain, has higher absorption when taken orally, and lasts longer in preventing acetylcholine breakdown.

6. Lion’s Mane

Lion's Mane (Hericium erinaceus) is a type of medicinal mushroom known for its distinctive appearance, resembling the mane of a lion. It has been used for centuries in traditional Chinese and Japanese medicine for its potential health benefits.

When mice were given hericene A (a compound from the Lion's Mane mushroom), their blood levels of pro-brain-derived neurotrophic factor (BDNF) increased. BDNF is a protein that plays a crucial role in the growth, development, maintenance, and survival of neurons in the brain. The same increase in BDNF was seen in overweight humans who took Lion's Mane extract, along with improvements in memory and mood.

Source: Leafie

7. Rhodiola Rosea

Rhodiola rosea, commonly known as Arctic root, golden root, rose root, or simply Rhodiola, is a plant in the Crassulaceae family. It is used for its potential adaptogenic and medicinal properties.

A comprehensive review and meta-analysis of preclinical studies were conducted to evaluate Rhodiola's effects on learning and memory. In the analysis, Rhodiola significantly increased the frequency and duration spent in the target quadrant in 23 studies, indicating better memory. Additionally, it decreased errors in memory tests in 6 studies, showing enhanced memory accuracy.

The possible mechanisms for these improvements include Rhodiola's antioxidant properties, regulation of the cholinergic system, anti-apoptosis (preventing cell death), anti-inflammatory effects, improved coronary blood flow, and enhanced cerebral metabolism.

8. Ashwagandha

Ashwagandha (Withania somnifera) is a medicinal herb widely used in Ayurvedic medicine, known for its ability to reduce stress, enhance cognitive function, boost energy, support the immune system, and promote overall health and well-being.

In a 2022 study, 13 healthy volunteers were given a series of mental tests to assess different aspects of brain function. They took either 400 mg of a placebo or 400 mg of ashwagandha extract. Experts found that the ashwagandha extract improved working memory (short-term memory used for immediate tasks) during the Sternberg Task test, especially after 3 and 6 hours.

Incorporating these ingredients into your memory supplement regimen can help support cognitive function and memory.

Top 11 Best Supplements for Memory and Focus

Finding the right supplements for memory and focus can greatly improve your cognitive abilities and mental wellness. To help you make an informed decision, we've curated a list of the best-rated supplements for boosting memory and focus. Our evaluation considered several crucial aspects:

  • Cost
  • Ingredients and their potency
  • Bioavailability
  • Additional benefits for overall cognitive health
  • Customer reviews and satisfaction

Explore our top picks for the best memory and focus supplements!

Disclaimer:

The details, information, and prices provided in this article are accurate as of the time of writing. These details may vary over time due to product updates, market changes, or other external influences. We recommend verifying any crucial information or prices with relevant sources, as fluctuations and updates are possible.


CHOQ Seven Wonders

CHOQ Seven Wonders

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CHOQ Seven Wonders is an exceptional memory supplement formulated with a blend of seven powerful adaptogenic mushrooms. These mushrooms, each known for their unique health benefits, include:

  • Organic Cordyceps
  • Reishi
  • Lion's Mane
  • Chaga
  • Turkey Tail
  • Maitake
  • King Oyster

Cordyceps stands out for its ability to boost learning and memory. Researchers tested its effects using mice with induced memory problems. The mice were given Cordyceps polypeptide and the results indicated that Cordyceps helped by reducing oxidative stress and protecting the nervous system. Moreover, Reishi is a great addition because it can help reduce stress, which significantly affects memory function. An animal study found that stress impairs spatial memory in rats.

This memory supplement is available for around $25 for a one-month supply. CHOQ Seven Wonders has also received positive feedback from users who appreciate its benefits in enhancing memory, focus, and overall well-being.

Pros

  • Comprehensive support on cognitive function and memory
  • Increases energy levels
  • Vegan and free from common allergens
  • Doesn't contain any harmful additives
  • High-quality mushroom complex supplement for memory
  • Also enhances immune system health, reduces inflammation, and provides antioxidant protection

Cons

  • Higher price point
  • Some users may experience digestive issues

Nature’s Craft Neuro Health Nootropic Complex

Nature’s Craft Neuro Health Nootropic Complex

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This nootropic complex from Nature's Craft is formulated to enhance memory, focus, and mental clarity. It contains 642 mg of a proprietary blend, which contains ingredients known for their cognitive benefits, such as Huperzine A, Dimethylaminoethanol (DMAE), Phosphatidylserine, and Bacopa Monnieri.

DMAE, in particular, helps increase levels of acetylcholine in the brain. This is because DMAE is a precursor to choline, and once in the brain, choline is converted into acetylcholine by the enzyme choline acetylase. Acetylcholine is a neurotransmitter that is involved in several brain functions, including memory and muscle control​.

A 30-day supply costs $19.55, and aside from its proprietary blend, this memory supplement contains other ingredients that support brain health and cognitive function. These are:

  • Vitamins A, C, D3, E
  • B vitamins (thiamine, riboflavin, niacin, folate, biotin, pyridoxine, and pantothenic acid)
  • Choline
  • Minerals (iron, magnesium, zinc, selenium, copper, manganese, chromium, and molybdenum)

Users have shared positive feedback, highlighting enhanced clarity in their thinking and an increased ability to articulate thoughts more efficiently. They appreciate the inclusion of essential vitamins and minerals, noting that these ingredients are commonly associated with boosting brain function. The ease of taking the supplement and the quick, visible results are other aspects that users value, alongside its ability to slow cognitive decline and facilitate easier word recall during conversations.

Pros

  • Contains ingredients like Inositol, Bilberry, and Huperzine A
  • Includes a mix of vitamins, minerals, and herbs for overall brain health
  • Great supplement for memory and brain fog
  • Formulated in GMPc facilities in the US and third-party tested for potency
  • Several users noticed a positive change in their memory

Cons

  • Contains soy and fish

The Genius Brand Genius Mushrooms

The Genius Brand Genius Mushrooms

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Genius Mushrooms is a supplement combining Lion’s Mane, Cordyceps, and Reishi mushrooms, designed to support cognitive function, boost natural energy, and enhance immune health. Priced at $23.99 for a 30-serving container, this product aims to offer several health benefits.

Many users experienced improved memory with Genius Mushrooms. They report enhanced mental clarity and the ability to remember details more easily, reaching into long-term memory with greater accuracy. The memory supplement's mood-boosting effects are also well-received, with users mentioning increased positivity and improved mood. They feel more relaxed and better able to manage stress, which contributes to overall mental well-being.

Pros

  • Suitable for keto, paleo, and vegan diets
  • Contains 500mg of each ingredient (lion’s mane, cordyceps, reishi)
  • Helps reduce stress and promotes relaxation
  • Supports cognitive function and memory
  • Boosts natural energy levels
  • Contains no carriers, fillers, artificial flavors, or GMOs

Cons

  • Higher price point
  • Manufactured in a facility that may also process milk, soy, wheat, egg, peanuts, tree nuts, fish, and shellfish

Double Wood Phosphatidylserine Supplement

Double Wood Phosphatidylserine Supplement

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Double Wood Supplements' PhosphatidylSerine, available for $24.95, features 300mg of phosphatidylserine per serving. This potent phospholipid is known for its role in supporting brain health, memory, and processing speed. Derived from soy lecithin, it aids in healthy stress levels and promotes glucose utilization, which is essential for cognitive functions.

Customers have reported significant improvements in their mental acuity, mood, and focus when using this memory supplement. They mention enhanced cognitive function and a calming effect in stressful situations. Many users have observed better short-term memory and faster recall without any negative impact on their memory.

Additionally, users appreciate the improved sleep quality, waking up refreshed and feeling more alert with sharper memory and increased vigor. The supplement is praised for its lack of adverse side effects and neuroprotective properties, contributing to reduced brain fog and mental fatigue.

Each bottle contains 120 capsules, providing a two-month supply when taken as recommended. It’s gluten-free, non-GMO, and rigorously tested for purity, ensuring you receive a high-quality supplement.

Pros

  • Positive user feedback regarding memory and cognitive function
  • Doesn’t come with any side effects
  • Gluten-free and non-GMO
  • Affordable price for a two-month supply
  • Helps lower cortisol levels

Cons

  • Contains soy making it unsuitable for soy-allergic individuals

Bronson Ginkgo Biloba Extra Strength Formula

Bronson Ginkgo Biloba Extra Strength Formula

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Bronson’s Ginkgo biloba Extract is an exceptional addition to your supplement regimen, priced at $9.99 for a bottle of 120 vegetarian capsules. This powerful formula contains 125mg of 4:1 Ginkgo biloba extract, equivalent to 500mg per serving.

Customer feedback highlights satisfaction with the quality and price of this memory supplement. Users frequently commend it as the best Ginkgo biloba they've tried, noting its effectiveness without issues. Many have observed enhanced memory, focus, and mental clarity. Additionally, its ease of swallowing, potency, and value for money are often praised.

Pros

  • Affordable price
  • Non-GMO, gluten-free and soy-free
  • Manufactured in a cGMP Certified New York Facility
  • Supports brain function, memory, and healthy circulation support

Cons

  • Some users reported side effects such as headaches, stomach issues, and heart palpitations

Dr. Emil Nutrition Lion’s Mane

Dr. Emil Nutrition Lion’s Mane

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Dr. Emil Nutrition Lion’s Mane is an excellent supplement for memory, available for $22.85. This high-potency supplement features 2100 mg of organic Lion’s Mane mushroom powder, enhanced with BioPerine, a black pepper extract that aids absorption. Lion’s Mane is known for its nootropic benefits, supporting mental clarity, focus, memory, and overall cognitive health.

Many users have shared overwhelmingly positive feedback about Dr. Emil Nutrition's memory supplement. They highlight significant improvements in focus, memory, and overall mental acuity. They even mention enhanced clarity, reduced anxiety, and a noticeable boost in energy levels. Plus, users note that it helps alleviate brain fog, resulting in clearer thinking and a heightened sense of awareness.

Pros

  • High-potency Lion’s Mane extract
  • Enhanced absorption with BioPerine
  • Vegan, gluten-free, and non-GMO
  • Boosts immunity and reduces inflammation

Cons

  • Higher price point
  • Large serving size of three capsules per day, which might be inconvenient for some

NOW Supplements Brain Elevate

NOW Supplements Brain Elevate

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NOW Supplements Brain Elevate™, priced at $14.65 for a bottle of 60 vegetarian capsules, combines a blend of brain-boosting ingredients scientifically formulated to promote healthy cerebral functions. This supplement features free radical scavengers, also known as antioxidants, to neutralize harmful molecules that can damage cells, including brain cells. NOW Supplements used RoseOx®, a trademarked rosemary extract owned by Hauser Inc. This company specializes in developing and commercializing natural products and botanical extracts.

In addition, this memory supplement also contains neuronal nutrients like Phosphatidylserine, Glutamine, and Choline, which are substances that provide essential nourishment to brain cells. These ingredients work synergistically to enhance cognitive performance, improve memory, and support overall brain health.

Users consistently praise Brain Elevate™ for enhancing concentration, memory, and cognitive recall. The product has been particularly noted for improving brain activity, helping individuals feel more alert and attentive. One satisfied customer shared, "I have been taking this supplement for a while now. I feel sharper and more alert." Others have expressed similar sentiments, emphasizing the noticeable improvements in their memory retention, attention span, and overall mental sharpness. Many users also report feeling more relaxed and less forgetful, underscoring the memory supplement's balanced approach to supporting brain health​.

Pros

  • Affordable price
  • Enhances memory and cognitive function
  • Includes powerful antioxidants, Ginkgo biloba and Rosemary Extract
  • Trusted brand with a reputation for quality
  • Suitable for vegetarians and vegans
  • Free from gluten, dairy, and nuts

Cons

  • Contains soy

OLLY Ultra Strength Brain Multi-Benefit Blend

OLLY Ultra Strength Brain Multi-Benefit Blend

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OLLY’s Ultra Strength Brain softgels are a premium nootropic supplement developed to boost your brain's health and performance. Retailing at $24.99 for a 30-day supply, these softgels include Bacopa Extract, Blueberry Extract, Omega-3 fatty acids, and Vitamins B6 and B12, which are important for supporting healthy brain cell activity.

These softgels are also designed with convenience in mind. They have a hint of peppermint flavor, are sugar-free, and come in a compact form that’s easy to carry and consume. However, they do contain allergens such as fish (anchovy and sardine), so it's important to consider this if you have allergies.

Many customers have observed noticeable benefits in their memory, making the supplement a comprehensive aid for overall brain health and performance. This positive feedback highlights the supplement's effectiveness in supporting various aspects of mental acuity and cognitive performance.

Pros

  • Supports focus and concentration
  • Sugar-free memory supplement with a pleasant peppermint flavor
  • Convenient and easy to take
  • Positive user feedback on efficacy

Cons

  • Higher price point
  • Some users experienced gastrointestinal issues
  • Several users didn’t like the smell and aftertaste due to the fish ingredient

Clean Nutraceuticals Cogni Defend All-in-1 Supplement

Clean Nutraceuticals Cogni Defend All-in-1 Supplement

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Clean Nutraceuticals All-in-One Cogni-Defend supplement, available for $24.95 (30 servings), combines Alpha GPC, Bacopa Monnieri, Ginkgo Biloba, Phosphatidylserine, and Huperzine A to support memory, focus, and overall brain function. Each capsule is also enriched with essential vitamins like C, D3, E, B6, and B12, as well as Omega-3 flax seed and antioxidants, ensuring comprehensive brain and immune support.

Additionally, the inclusion of Lion's Mane Mushroom and Uridine 5-Monophosphate (UMP) in this memory supplement provides neuroprotective benefits and supports brain cell regeneration. Studies show that adults don’t get enough uridine from their diet alone, and no food has been proven to raise uridine levels in the blood significantly.

Many have experienced enhanced mental energy and even improved critical thinking abilities with this all-in-one supplement. Additionally, customers noted feeling more alert, focused, and clear-headed. Some mentioned noticing immediate improvements in their memory and cognitive functions, making it a popular choice for those seeking mental clarity and enhanced brain performance.

Pros

  • Enhances critical thinking abilities
  • Complete with essential vitamins and antioxidants
  • Positive user feedback on cognitive improvements
  • High-quality, rigorously tested ingredients
  • Contains black pepper for enhanced bioavailability

Cons

  • Higher price point
  • Few users experienced difficulty sleeping after taking the supplement

Four Sigmatic Memory Mushroom Complex

Four Sigmatic Memory Mushroom Complex

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Four Sigmatic's mushroom complex, priced at $24.89, is another memory and focus supplement that features Cordyceps, Turmeric, Gotu Kola, and Ashwagandha, all known for their remarkable brain-boosting properties. These ingredients are organically sourced and meticulously processed to retain their full potency and benefits.

Users have praised this memory supplement for its immediate effects, reporting enhanced focus, improved memory recall, and a noticeable reduction in brain fog.

Pros

  • Specifically formulated to enhance memory
  • Contains other ingredients with antioxidant properties
  • Organic and high-quality ingredients
  • Supports long-term brain health

Cons

  • Higher price point
  • Large serving size (three capsules per day)

Garden of Life Memory & Focus

Garden of Life Memory & Focus

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The Garden of Life Dr. Formulated Memory & Focus is one of the best supplements for cognitive function for adults aged 40 years and older. Priced at $30.39, this supplement offers excellent value for its potent blend of clinically studied and organic ingredients aimed at enhancing memory, focus, and clear thinking.

The key ingredients include Organic Neurophenol™, a blend of organic grape and wild blueberry, known for their antioxidant properties that support brain health. Another significant component is Organic NeuroFactor™, derived from whole coffee fruit, which is clinically proven to increase levels of Brain-Derived Neurotrophic Factor (BDNF), vital for cognitive function and memory.

The formula also includes an Organic Brain Health Lipid Blend, combining powdered coconut and avocado oils. These healthy fats help fat-soluble ingredients to be absorbed in the gut and assist with their assimilation into tissues.

Users have shared positive feedback about this memory supplement. Many have noticed significant improvements in memory sharpness and their ability to process and recall information more effectively. They appreciate the enhanced focus and mental clarity the supplement provides, highlighting it as a valuable tool for maintaining cognitive health.

Pros

  • Certified USDA organic & non-GMO
  • Vegetarian, gluten-free, dairy-free, soy-free
  • Improves memory, focus, and concentration
  • Specifically formulated for adults 40+

Cons

  • Expensive
  • Few users complained about the size of the tablets saying that they are difficult to swallow

Takeaway

Choosing the right memory supplement can significantly enhance your cognitive function and overall brain health. CHOQ Seven Wonders is among the best memory supplements. Its blend of seven adaptogenic mushrooms supports cognitive health, improves immune response, and reduces inflammation.

Meanwhile, Nature’s Craft Neuro Health Nootropic Complex stands out for its blend of Huperzine A, DMAE, Phosphatidylserine, and Bacopa Monnieri, which collectively boost memory, focus, and mental clarity.

Genius Mushrooms by The Genius Brand is another excellent option. It offers the benefits of Lion’s Mane, Cordyceps, and Reishi mushrooms, similar to those of CHOQ Seven Wonders.

Enhance your cognitive health today by choosing one of these top-rated memory supplements and experience the benefits of sharper memory, improved focus, and overall brain health.

FAQs on Memory Supplements

Do memory supplements help with age-related cognitive decline?

Some memory supplements may help with age-related cognitive decline. Ingredients like phosphatidylserine and certain vitamins have shown promise in supporting brain health in older adults. For instance, a meta-analysis of 95 studies, each spanning at least 12 months, indicates that B vitamin supplementation can help slow cognitive decline, particularly in individuals who receive early and long-term intervention.

Do memory supplements need to be taken daily?

Most memory supplements are intended to be taken daily to maintain consistent levels of the active ingredients in your system. Adhering to the recommended dosage schedule is important to achieve the best results.

Are there any age restrictions for taking memory supplements?

Memory supplements are typically formulated for adults, and their safety for children or adolescents may not be well-established. It's important to follow the age recommendations on the product label and consult with a healthcare provider before giving any supplements to younger individuals.

Are natural memory supplements better than synthetic ones?

Natural memory supplements often appeal to those looking for holistic or less processed options. They typically contain herbs, vitamins, and minerals derived from natural sources. However, synthetic supplements can also be effective and are usually standardized to provide consistent dosages. The best choice depends on individual preferences and needs.

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